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  5. Synaptophysin-like protein 2

Tbio Synaptophysin-like protein 2

Involved in communication between the T-tubular and junctional sarcoplasmic reticulum (SR) membranes.

 Comments

Property Summary

NCBI Gene PubMed Count 10
PubMed Score 24.68
PubTator Score 7.33

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (4)

Disease Target Count P-value
psoriasis 6694 4.9e-49
group 3 medulloblastoma 4104 9.1e-04
subependymal giant cell astrocytoma 2287 3.0e-02
Disease Target Count Z-score Confidence
Carcinoma 11493 0.0 0.6
Disease Target Count Z-score Confidence
Kidney disease 430 0.0 3.0
Disease Target Count Z-score Confidence
Central core myopathy 5 3.275 1.6

Expression

  Differential Expression (3)

Disease log2 FC p
group 3 medulloblastoma -1.500 9.1e-04
psoriasis -2.700 4.9e-49
subependymal giant cell astrocytoma 1.021 3.0e-02

Synonym

Accession Q5VXT5 A8K0E8 A8KAL7 I0IT67 Q6ZMX1
Symbols MG29

Gene

SYPL2

PANTHER Protein Class (2)

  Ortholog (1)

Species Source Disease
Mouse OMA Inparanoid

 UniProt Keyword (7)

 GO Function (1)

 GO Component (1)

 GO Process (2)

 Compartment GO Term (47)

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 MGI Phenotype (2)

 GWAS Trait (4)

 HCA RNA Cell Line (51)

See all...

Protein-protein Interaction (11)

HSPA5   TMEM192   SYNGR2   RTN2   VAMP3   GCA   TSPAN15   NECTIN2   MFSD12   REEP6   TMEM120A  

Gene RIF (2)

AA Sequence 

MSSTESAGRTADKSPRQQVDRLLVGLRWRRLEEPLGFIKVLQWLFAIFAFGSCGSYSGETGAMVRCNNEA      1 - 70
KDVSSIIVAFGYPFRLHRIQYEMPLCDEESSSKTMHLMGDFSAPAEFFVTLGIFSFFYTMAALVIYLRFH     71 - 140
NLYTENKRFPLVDFCVTVSFTFFWLVAAAAWGKGLTDVKGATRPSSLTAAMSVCHGEEAVCSAGATPSMG    141 - 210
LANISVLFGFINFFLWAGNCWFVFKETPWHGQGQGQDQDQDQDQGQGPSQESAAEQGAVEKQ            211 - 272
//

Text Mined References (10)

PMID Year Title