Tbio SFMBT2 Scm-like with four MBT domains protein 2

Protein Summary

Description

Transcriptional repressor of HOXB13 gene.

Uniprot Accession IDs

• Q5VUG0
• A7MD09
• Q9HCF5
• Scm-like with 4 MBT domains protein 2

Gene Name

• SFMBT2

Ensembl ID

• ENST00000361972
• ENSP00000355109
• ENSG00000198879
• ENST00000397167
• ENSP00000380353

Symbol

• KIAA1617

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor	0.76
protein domain	0.73
PubMedID	0.73
tissue sample	0.73
transcription factor binding site profile	0.73

Protein Classes

PANTHER Classes

Protein / Transcription Factor / Scm-like With Four Mbt Domains Protein 2

Protein / Nucleic Acid Binding / Dna Binding Protein / Chromatin/chromatin-binding Protein / Scm-like With Four Mbt Domains Protein 2

DTO Classes

Protein / Nucleic Acid Binding / Dna Binding Protein / Chromatin/chromatin-binding Protein / Scm-like With Four Mbt Domains Protein 2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 29.48   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 32   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 29.48   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 32   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0