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Tbio
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1

Protein Summary
Description
May play an essential role for the assembly of the mitochondrial F1-F0 complex. This gene encodes an assembly factor for the F(1) component of the mitochondrial ATP synthase. This protein binds specifically to the F1 beta subunit and is thought to prevent this subunit from forming nonproductive homooligomers during enzyme assembly. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Aug 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000532925
  • ENSP00000435732
  • ENSG00000123472
  • ENST00000542495
  • ENSP00000443588
  • ENST00000574428
  • ENSP00000459167

Symbol
  • ATP11
  • ATP11
  • ATP11p
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.74
histone modification site profile
0.73
tissue
0.69
microRNA
0.62
transcription factor binding site profile
0.6


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.95   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 80   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.95   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 80   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0