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Tdark RNA-binding protein 26


 Comments

Property Summary

NCBI Gene PubMed Count 15
PubMed Score 0.70
PubTator Score 0.40

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (3)

Disease Target Count P-value
juvenile dermatomyositis 1189 1.39307326684257E-8
ovarian cancer 8492 1.2878353246713E-7
osteosarcoma 7933 2.81053014426166E-7
glioblastoma 5572 1.89007076628277E-5
tuberculosis and treatment for 6 months 686 2.66665966147276E-5
Pick disease 1893 2.22542226481199E-4
dermatomyositis 967 7.41065882312039E-4
malignant mesothelioma 3163 0.00105363535891625
ependymoma 2514 0.012109151676281
progressive supranuclear palsy 674 0.0166806537519159
intraductal papillary-mucinous neoplasm (IPMN) 3289 0.022866504311633
intraductal papillary-mucinous adenoma (IPMA) 2956 0.0278712734799083
oligodendroglioma 2849 0.0356095671958773
Disease Target Count Z-score Confidence
Costello Syndrome 18 3.942 2.0
Beckwith-Wiedemann syndrome 46 3.356 1.7

Expression

  Differential Expression (13)

Disease log2 FC p
malignant mesothelioma 1.100 0.001
ependymoma 1.400 0.012
oligodendroglioma 1.100 0.036
osteosarcoma 2.055 0.000
glioblastoma -1.400 0.000
juvenile dermatomyositis 1.063 0.000
tuberculosis and treatment for 6 months 1.400 0.000
intraductal papillary-mucinous adenoma (... 1.100 0.028
intraductal papillary-mucinous neoplasm ... 1.600 0.023
Pick disease -1.800 0.000
progressive supranuclear palsy -1.500 0.017
ovarian cancer -1.800 0.000
dermatomyositis 1.100 0.001

Synonym

Accession Q5T8P6 B4DZE0 Q2NKM2 Q2NKQ2 Q5CZH8 Q5T8P5 Q5T8P8 Q5U5P5 Q5W0G7 Q8N3H5 Q96K92 Q96SZ3 Q9H2F8 Q9H7F9 Q9P1G7
Symbols ARRS2
SE70-2
ZC3H17
PRO1777
C13orf10
PPP1R132

Gene

RBM26

PANTHER Protein Class (2)

  Ortholog (12)

Species Source
Macaque OMA Inparanoid
Mouse OMA EggNOG Inparanoid
Rat OMA EggNOG
Dog OMA EggNOG Inparanoid
Horse OMA EggNOG Inparanoid
Cow OMA EggNOG Inparanoid
Pig OMA Inparanoid
Opossum OMA Inparanoid
Platypus OMA EggNOG Inparanoid
Chicken OMA EggNOG Inparanoid
Anole lizard OMA EggNOG Inparanoid
Xenopus OMA Inparanoid

 GO Function (3)

 GO Process (2)

 Compartment GO Term (11)

 GWAS Trait (1)

 HCA RNA Cell Line (56)

See all...

Pathway (1)

 UniProt Keyword (14)

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Gene RIF (2)

PMID Text
25631074 Cellular biotinylated RNA binding motif protein 26 (RBM26) is incorporated into HIV-1 Gag virus-like particles
20379614 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

AA Sequence 

MVSKMIIENFEALKSWLSKTLEPICDADPSALAKYVLALVKKDKSEKELKALCIDQLDVFLQKETQIFVE      1 - 70
KLFDAVNTKSYLPPPEQPSSGSLKVEFFPHQEKDIKKEEITKEEEREKKFSRRLNHSPPQSSSRYRENRS     71 - 140
RDERKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRERDRDRSRTRSRSRTRS    141 - 210
RERDLVKPKYDLDRTDPLENNYTPVSSVPSISSGHYPVPTLSSTITVIAPTHHGNNTTESWSEFHEDQVD    211 - 280
HNSYVRPPMPKKRCRDYDEKGFCMRGDMCPFDHGSDPVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPP    281 - 350
PILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPP    351 - 420
SLFTADTYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLPPREKPPNKSSMRIVVDSESR    421 - 490
KRTIGSGEPGVPTKKTWFDKPNFNRTNSPGFQKKVQFGNENTKLELRKVPPELNNISKLNEHFSRFGTLV    491 - 560
NLQVAYNGDPEGALIQFATYEEAKKAISSTEAVLNNRFIKVYWHREGSTQQLQTTSPKVMQPLVQQPILP    561 - 630
VVKQSVKERLGPVPSSTIEPAEAQSASSDLPQNVTKLSVKDRLGFVSKPSVSATEKVLSTSTGLTKTVYN    631 - 700
PAALKAAQKTLLVSTSAVDNNEAQKKKQEALKLQQDVRKRKQEILEKHIETQKMLISKLEKNKTMKSEDK    701 - 770
AEIMKTLEVLTKNITKLKDEVKAASPGRCLPKSIKTKTQMQKELLDTELDLYKKMQAGEEVTELRRKYTE    771 - 840
LQLEAAKRGILSSGRGRGIHSRGRGAVHGRGRGRGRGRGVPGHAVVDHRPRALEISAFTESDREDLLPHF    841 - 910
AQYGEIEDCQIDDSSLHAVITFKTRAEAEAAAVHGARFKGQDLKLAWNKPVTNISAVETEEVEPDEEEFQ    911 - 980
EESLVDDSLLQDDDEEEEDNESRSWRR                                               981 - 1007
//

Text Mined References (25)

PMID Year Title
25416956 2014 A proteome-scale map of the human interactome network.
25114211 2014 Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.
24275569 2014 An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
23186163 2013 Toward a comprehensive characterization of a human cancer cell phosphoproteome.
22681889 2012 The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
22658674 2012 Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
21406692 2011 System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
21269460 2011 Initial characterization of the human central proteome.
20379614 Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
20068231 2010 Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
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