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Tbio
FKBP15
FK506-binding protein 15

Protein Summary
Description
May be involved in the cytoskeletal organization of neuronal growth cones. Seems to be inactive as a PPIase (By similarity). Involved in the transport of early endosomes at the level of transition between microfilament-based and microtubule-based movement.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000238256
  • ENSP00000238256
  • ENSG00000119321

Symbol
  • KIAA0674
  • FKBP133
  • PPP1R76
  • KIAA0674
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
drug perturbation
1
histone modification site profile
0.89
protein complex
0.86
disease perturbation
0.83
tissue sample
0.79


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.76   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 86   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.76   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 86   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0