Property Summary

NCBI Gene PubMed Count 10
PubMed Score 43.78
PubTator Score 3.50

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (3)

Disease Target Count P-value
osteosarcoma 7933 4.94406275223292E-7
ovarian cancer 8492 1.70667858935458E-6
lung cancer 4473 6.03582708940475E-4
medulloblastoma, large-cell 6234 0.00250555512063721
intraductal papillary-mucinous neoplasm (IPMN) 3289 0.0108273835038099
inflammatory breast cancer 404 0.0373884620962175
Disease Target Count Z-score Confidence
Parkinson's disease 364 3.846 1.9
Disease Target Count Z-score Confidence
REM sleep behavior disorder 16 3.92 2.0

Expression

  Differential Expression (6)

Disease log2 FC p
osteosarcoma -2.301 0.000
medulloblastoma, large-cell -1.100 0.003
intraductal papillary-mucinous neoplasm ... -1.200 0.011
lung cancer -1.100 0.001
inflammatory breast cancer -1.200 0.037
ovarian cancer -1.100 0.000

Synonym

Accession Q5T013 D3DPX4 D3DPX5 Q5Q9A2 Q7Z778 Q96S83 Q9BZR3 Q9BZR4
Symbols HT036

Gene

HYI

PANTHER Protein Class (2)

  Ortholog (10)

Species Source
Chimp OMA EggNOG
Macaque OMA EggNOG Inparanoid
Rat OMA EggNOG Inparanoid
Cow OMA EggNOG
Opossum EggNOG Inparanoid
Platypus OMA EggNOG Inparanoid
Anole lizard OMA EggNOG Inparanoid
Xenopus OMA EggNOG Inparanoid
C. elegans OMA EggNOG Inparanoid
Fruitfly OMA EggNOG Inparanoid

Gene RIF (1)

PMID Text
22490543 Protein HYI may closely bind with protein P311 by an alpha helix in hypertrophic scar fibroblasts.

AA Sequence

MAPLRFSANLSWLFPELSGLPARVRAAGSSGFEAVEVAWPYAETPEALARAAREAGLRLVLINTPPGDQE      1 - 70
KGEMGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENLRHAAGVL     71 - 140
AQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIMDGNLTGNIREFLPIVGH    141 - 210
VQVAQVPGRGEPSSPGELNFPYLFQLLEDEGYKGFVGCEYQPRGDTVEGLSWLRSYWDRRGHPEAGQ       211 - 277
//

Text Mined References (13)

PMID Year Title
25416956 2014 A proteome-scale map of the human interactome network.
22490543 2012 [Analysis of the binding domain of hydroxypyruvate isomerase homologues in hypertrophic scar fibroblasts].
19722193 2009 Low concentration of anti-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene induces alterations of extracellular protein profile of exposed epithelial cells.
17207965 2007 hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.
16710414 2006 The DNA sequence and biological annotation of human chromosome 1.
16341674 2005 Transcriptome analysis of human gastric cancer.
16189514 2005 Towards a proteome-scale map of the human protein-protein interaction network.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
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