Property Summary

NCBI Gene PubMed Count 2
PubMed Score 0.47

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (2)

Disease Target Count P-value
oligodendroglioma 2849 6.74678688217598E-23
atypical teratoid / rhabdoid tumor 4369 3.8972928156673E-10
sonic hedgehog group medulloblastoma 1482 1.14841491765628E-7
pilocytic astrocytoma 3086 1.10023250229813E-6
posterior fossa group A ependymoma 1511 1.91759395137191E-6
pediatric high grade glioma 2712 6.83643468451034E-6
lung adenocarcinoma 2714 9.93089565385392E-6
nasopharyngeal carcinoma 1056 1.79295754713533E-5
glioblastoma 5572 5.20194264449626E-5
Breast cancer 3099 7.40836760297367E-4
pituitary cancer 1972 9.125072474257E-4
astrocytic glioma 2241 0.00119252358980339
primitive neuroectodermal tumor 3031 0.00156782026417784
lung carcinoma 2844 0.00658782955122023
Endometriosis 535 0.0111243627256829
Pick disease 1893 0.0119017941330837
medulloblastoma, large-cell 6234 0.01638481518558
subependymal giant cell astrocytoma 2287 0.0166075010226358
ileal Crohn's disease 9 0.0492035367512846
chronic rhinosinusitis 512 0.0492232394336676
Disease Target Count Z-score Confidence
Carcinoma 2147 0.0 1.0

Expression

  Differential Expression (20)

Disease log2 FC p
astrocytic glioma -3.600 0.001
oligodendroglioma -3.300 0.000
glioblastoma -3.800 0.000
posterior fossa group A ependymoma -2.200 0.000
sonic hedgehog group medulloblastoma -4.400 0.000
atypical teratoid / rhabdoid tumor -5.000 0.000
medulloblastoma, large-cell -3.100 0.016
primitive neuroectodermal tumor -3.100 0.002
lung adenocarcinoma -1.200 0.000
pediatric high grade glioma -3.300 0.000
pilocytic astrocytoma -3.300 0.000
subependymal giant cell astrocytoma -2.652 0.017
nasopharyngeal carcinoma -3.200 0.000
Endometriosis -1.126 0.011
lung carcinoma 1.400 0.007
Pick disease -2.200 0.012
Breast cancer -1.600 0.001
ileal Crohn's disease -1.252 0.049
pituitary cancer 1.300 0.001
chronic rhinosinusitis -2.216 0.049

Gene RIF (1)

PMID Text
20379614 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

AA Sequence

MSHSHPAGLLAAYNSLMDKHLAGYFNNTRIRRHLLRSGLITRSGRILSEKEYKLNMMKRDHQKYIRECLA      1 - 70
QAIFHKVLDMERYHQLEIKKKLETLARKERIQRFKGEHTRRSVENNMPILSPHPPVGPKSNRGHSVLVDE     71 - 140
GHSSPLALTAPRPYTAPGNMQPPIRLQPLPSNPAVETVPKVTSRSRSKTSLLENEALFPIGGKKAVMKFR    141 - 210
NSIGNSQRMNSYQLPNINSYMMPIPPPLPPTGKITRENRSETWRRRRFRPTTAPNGLEPLLTKDSRRIHK    211 - 280
TSLHSNAAITMIYLGKNVHLSSDNPDFRDEIKVYQQHCGGENLCVYKGKLLEKETFQFISKRHHGFPFSL    281 - 350
TFFLNGMQVNRLSSCCEYKHRKGSRLGGKRGYFGFVCVERSSPCYKCIIAMGLDKKPSLPKSRKEKSTEK    351 - 420
GEELKKAEGKVRKEREYVIPKRNEIKENKTSVSAKFSAQEIKTGLKEVVTAVEEMTSKGKPGQEVLEDDQ    421 - 490
ENTLKYEYEEDFEVDEEKQGEKSNEEGQADVQMNGIPQSPLDDKKDNLDPEKESETSSQKAPDARDNVKD    491 - 560
ENDGCSESELEEDKQDMKTASSTSSRSHPYSSDSEDESAVGDREAHTDSSTDESARRSSSQELSENDKPR    561 - 630
KSHLPIEESLEIEIEDQEITKADVETKPMPIDESFENVLKEGTEKGTQEIAEGLSEKSGKHVSAEEKEKD    631 - 700
KSKLWEESTAQVKDKKAGLPGLEEGGKDSLPLAYVLALGAPTMNFMVDETAAINSNKESQQLVQKTYTLE    701 - 770
KKEAMEEDEAPQHRDADIVQGKGEAALWGEAGAVHEAPLRAWKPTAEQPELAEEFTEKREIPPGIERGAE    771 - 840
GAAEAEGVRRLGEGGSDPIGQAAAKDAVGLSKDEAPEKQALMLTVLETDKAASEGEQGLEKAVLANEAAA    841 - 910
LNLEHLHEVAALREAATSEEGEAEGGVAVSDVGESEEEASIDLEDTGPMEDTASKREDGSEEAILGGEEP    911 - 980
AKERKEVMRTETRLSPFTGEAEASRMQVSEGSPEEGSLAKEAFLCKEDVEGEEMVTEAEANREDDRKEIL    981 - 1050
PKELDLARERRKAERPKTSLRKTDSEREEVTRANALKDEDAFKEEQKLKAEEGETETEVRAEEETKAPPN   1051 - 1120
EMGSDAENEAPVEASELSDNPGLLGEDSLKETVVPIFEATPGFEKSLENITALRKEGGGERLSEARDTEH   1121 - 1190
KDREELSSRENRALKEGHRQDGEGALAAPEAEPAGKVQAPEGLIPATGQAEELAAKDHDSCAGLEGRAEG   1191 - 1260
QGGVDVVLRTQEAVAEEDPIMAEKFREEAVDEDPEEEEDKECTLETEAMQDRNSEGDGDMEGEGNTQKNE   1261 - 1330
GMGGGRVVAVEVLHGGGETAETAAEEREVLAGSETAEEKTIANKASSFSDVAEEETWHQQDELVGKTAAA   1331 - 1400
GKVVVEELARSGEEVPAAEEMTVTYTTEAGVGTPGALERKTSGLGQEQEEGSEGQEAATGSGDGRQETGA   1401 - 1470
AEKFRLGLSREGERELSPESLQAMATLPVKPDFTETREKQQHMVQGESETADVSPNNVQV             1471 - 1530
//

Text Mined References (6)

PMID Year Title
20379614 Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
17974005 2007 The full-ORF clone resource of the German cDNA Consortium.
16710414 2006 The DNA sequence and biological annotation of human chromosome 1.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.