Tdark ZNF628 Zinc finger protein 628

Protein Summary

Description

Transcription activator. Binds DNA on GT-box consensus sequence 5'-TTGGTT-3' (By similarity). Zinc finger proteins (ZNFs), which bind nucleic acids, perform many key functions, the most important of which is regulating transcription. See ZNF91 (MIM 603971) for general information on ZNFs.[supplied by OMIM, Mar 2008]

Uniprot Accession IDs

• Q5EBL2
• Q86X34

Gene Name

• ZNF628

Ensembl ID

• ENST00000598519
• ENSP00000469591
• ENSG00000197483

Symbol

• ZEC
• Zfp628

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.68
cell line	0.59
transcription factor binding site profile	0.59
tissue sample	0.57
virus perturbation	0.5

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.9   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 20   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.9   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 20   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0