Property Summary

NCBI Gene PubMed Count 12
PubMed Score 4.36
PubTator Score 6.03

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (23)

Disease log2 FC p
astrocytic glioma -2.900 0.001
posterior fossa group A ependymoma -4.400 0.000
oligodendroglioma -2.600 0.014
glioblastoma -4.200 0.000
osteosarcoma 2.128 0.032
sonic hedgehog group medulloblastoma -3.300 0.000
atypical teratoid / rhabdoid tumor -2.500 0.015
medulloblastoma, large-cell -3.100 0.007
primitive neuroectodermal tumor -4.100 0.000
non-small cell lung cancer -3.430 0.000
interstitial cystitis -1.200 0.004
lung adenocarcinoma -1.500 0.000
adult high grade glioma -3.500 0.000
pilocytic astrocytoma -3.000 0.000
aldosterone-producing adenoma -1.370 0.027
subependymal giant cell astrocytoma -3.594 0.001
lung carcinoma -2.500 0.000
Pick disease -1.300 0.010
gastric carcinoma -3.600 0.006
invasive ductal carcinoma -1.300 0.017
ovarian cancer -1.300 0.000
pituitary cancer 1.400 0.001
psoriasis -1.200 0.000

Gene RIF (8)

PMID Text
24599690 The study found significant associations between autism and two SNPs of the ZNF533 gene.
23029477 ZNF385B and VEGFA are strongly differentially expressed in serous ovarian carcinomas and correlate with survival.
22945289 The direct binding of ZNF385B with p53 has suggested the involvement of ZNF385B in B-cell apoptosis via modulation of p53 transactivation
20849254 the relationship between ZNF533, environmental factors, and the etiology of nonsyndromic orofacial clefts
20849254 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
20379614 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
19401682 Observational study of gene-disease association. (HuGE Navigator)
19240061 Observational study of gene-disease association. (HuGE Navigator)

AA Sequence

MNMANFLRGFEEKGIKNDRPEDQLSKEKKKILFSFCEVCNIQLNSAAQAQVHSNGKSHRKRVKQLSDGQP      1 - 70
PPPAQASPSSNSSTGSTCHTTTLPALVRTPTLMMQPSLDIKPFMSFPVDSSSAVGLFPNFNTMDPVQKAV     71 - 140
INHTFGVSIPPKKKQVISCNVCQLRFNSDSQAEAHYKGSKHAKKVKALDATKNKPKMVPSKDSAKANPSC    141 - 210
SITPITGNNSDKSEDKGKLKASSSSQPSSSESGSFLLKSGTTPLPPGAATSPSKSTNGAPGTVVESEEEK    211 - 280
AKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKMQNGSKGSGLQNKTFHC    281 - 350
EICDVHVNSEIQLKQHISSRRHKDRVAGKPLKPKYSPYNKLQRSPSILAAKLAFQKDMMKPLAPAFLSSP    351 - 420
LAAAAAVSSALSLPPRPSASLFQAPAIPPALLRPGHGPIRATPASILFAPY                       421 - 471
//

Text Mined References (14)

PMID Year Title
26755636 2016 Exome sequencing and CRISPR/Cas genome editing identify mutations of ZAK as a cause of limb defects in humans and mice.
24599690 2014 Family-based association study of ZNF533, DOCK4 and IMMP2L gene polymorphisms linked to autism in a northeastern Chinese Han population.
24275569 2014 An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
23029477 2012 ZNF385B and VEGFA are strongly differentially expressed in serous ovarian carcinomas and correlate with survival.
22945289 2012 ZNF385B is characteristically expressed in germinal center B cells and involved in B-cell apoptosis.
21658281 2011 GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.
20849254 2011 Significant evidence of association between polymorphisms in ZNF533, environmental factors, and nonsyndromic orofacial clefts in the Western Han Chinese population.
20379614 Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
19401682 2010 High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility.
19240061 2009 Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.
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