Tbio MPV17L2 Mpv17-like protein 2

Protein Summary

Description

Required for the assembly and stability of the mitochondrial ribosome (PubMed:24948607). Is a positive regulator of mitochondrial protein synthesis (PubMed:24948607).

Uniprot Accession IDs

• Q567V2
• Q96P34
• Q96QA0
• Q9BSG4

Gene Name

• MPV17L2

Ensembl ID

• ENST00000599612
• ENSP00000469836
• ENSG00000254858

Symbol

• FKSG24
• FKSG24

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.91
tissue sample	0.65
cell type or tissue	0.61
cellular component	0.59
phenotype	0.56

Protein Classes

PANTHER Classes

Protein / Transmembrane Receptor Regulatory/adaptor Protein / Mpv17-like Protein 2

DTO Classes

Protein / Receptor / Mpv17-like Protein 2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.62   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 32   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.62   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 32   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0