Protein Summary
Negative regulator of sphingolipid synthesis.
- ENST00000243045
- ENSP00000243045
- ENSG00000123353
- ENST00000548974
- ENSP00000448788
- MST095
- HSPC160
- MSTP095
- adoplin-2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 0.96 | ||
histone modification site profile | 0.77 | ||
transcription factor perturbation | 0.74 | ||
virus perturbation | 0.68 | ||
transcription factor | 0.57 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2.09 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 80 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2.09 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 80 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0