SLC9B1
Sodium/hydrogen exchanger 9B1
Protein Summary
Sperm-specific Na(+)/H(+) exchanger involved in intracellular pH regulation of spermatozoa. Involved in sperm motility and fertility. The protein encoded by this gene is a sodium/hydrogen exchanger and transmembrane protein. Highly conserved orthologs of this gene have been found in other mammalian species. The expression of this gene may be limited to testis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
- ENST00000296422
- ENSP00000296422
- ENSG00000164037
- ENST00000394789
- ENSP00000378269
- ENST00000503584
- ENSP00000426926
- ENST00000510243
- ENSP00000425913
- NHA1
- NHEDC1
- NHA1
- NHEDC1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
histone modification site profile | 0.78 | ||
transcription factor perturbation | 0.61 | ||
kinase perturbation | 0.6 | ||
tissue sample | 0.6 | ||
cell type or tissue | 0.58 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 115.72 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 89 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 115.72 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 89 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0