Property Summary

NCBI Gene PubMed Count 8
PubMed Score 0.00

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (1)

Disease Target Count P-value
lung carcinoma 2844 3.74901646125474E-34
ovarian cancer 8492 7.07771141271643E-10
malignant mesothelioma 3163 1.07886585142414E-6
lung cancer 4473 2.36267999165603E-6
tuberculosis 1563 3.59443026946908E-5
medulloblastoma, large-cell 6234 0.0016388575738769
osteosarcoma 7933 0.00415403899778775
group 3 medulloblastoma 2254 0.0133418729242979
invasive ductal carcinoma 2950 0.0293281788384422

Expression

  Differential Expression (9)

Disease log2 FC p
malignant mesothelioma 2.600 0.000
osteosarcoma 1.077 0.004
medulloblastoma, large-cell 1.100 0.002
tuberculosis -1.400 0.000
lung cancer -3.600 0.000
group 3 medulloblastoma -1.100 0.013
invasive ductal carcinoma -1.135 0.029
lung carcinoma -2.500 0.000
ovarian cancer 1.400 0.000

Synonym

Accession Q496Y0 Q5JPN6 Q8NB00 Q9H647
Symbols RNF127

Gene

  Ortholog (10)

Gene RIF (1)

PMID Text
23898208 HIV-1 Tat downregulates the expression of LON peptidase N-terminal domain and ring finger 3 (LONRF3) in human primary T cells

AA Sequence

MESVRIEQMLSLPAEVSSDNLESAERGASAAQVDMGPHPKVAAEGPAPLPTREPEQEQSPGTSTPESKVL      1 - 70
LTQADALASRGRIREALEVYRQLSERQQLVAEQLEQLVRCLAEKVPQGEALAPAPPDEGSTASGTVAAEE     71 - 140
TGAAAAAAATEVWDGFKCRKCHGFLSDPVSLSCGHTFCKLCLERGRAADRRCALCGVKLSALMVATGRAR    141 - 210
GARRAGQQPPPPLRVNVVLSGLLGKLFPGPARASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLY    211 - 280
SNRSQIYFTLESHENALHDAEIACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNKRARCE    281 - 350
AQRDNLELPHCSSQEEAAARGDGSSLMDPAKVKGDGQQHHMKDQEEEEEKWDATSPKAASSKTGKCQEKK    351 - 420
RKHCQIESQEETGMPNKASKQDPPTDQGDKPALSLPLASFDASDLECALCMRLFYEPVTTPCGHTFCLKC    421 - 490
LERCLDHNAKCPLCKDGLSQCLASRKYSKNVIMEELIAKFLPEELKERRKLYEEEMEELSNLNKNVPIFV    491 - 560
CTMAYPTVPCPLHIFEPCYRLMIRRCIETGTRQFGMCLGDPVKGFAEYGCILEIRNVQFFADGRSVVDSI    561 - 630
GKRRFRVLHQSQRDGYNTADIEYIEDQKVQGEDCAELMGLHNCVYQQASLWFHSLKLSLKNRILNHFGPM    631 - 700
PEKDADPQMNPNGPAWCWWMLAVLPLESRAQLPFLAMRSLKDRLNGIRRVLAFISRNQN               701 - 759
//

Text Mined References (9)

PMID Year Title
25416956 2014 A proteome-scale map of the human interactome network.
20195357 2010 A comprehensive resource of interacting protein regions for refining human transcription factor networks.
16959974 2006 The consensus coding sequences of human breast and colorectal cancers.
15772651 2005 The DNA sequence of the human X chromosome.
15761153 2005 High-throughput mapping of a dynamic signaling network in mammalian cells.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
8744354 1996 Does this have a familiar RING?