Tbio BSX Brain-specific homeobox protein homolog

Protein Summary

Description

DNA binding protein that function as transcriptional activator. Is essential for normal postnatal growth and nursing. Is an essential factor for neuronal neuropeptide Y and agouti-related peptide function and locomotory behavior in the control of energy balance (By similarity).

Uniprot Accession IDs

• Q3C1V8

Gene Name

• BSX

Ensembl ID

• ENST00000343035
• ENSP00000344285
• ENSG00000188909

Symbol

• BSX1
• BSX1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue	0.74
cell type or tissue	0.65
protein domain	0.58
biological process	0.57
cell line	0.47

Protein Classes

PANTHER Classes

Protein / Transcription Factor / Helix-turn-helix Transcription Factor / Homeodomain Transcription Factor / Brain-specific Homeobox Protein Homolog

Protein / Nucleic Acid Binding / Dna Binding Protein / Brain-specific Homeobox Protein Homolog

DTO Classes

Protein / Transcription Factor / Helix-turn-helix Transcription Factor / Homeodomain Transcription Factor / Brain-specific Homeobox Protein Homolog

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 60.05   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 90   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 60.05   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 90   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0