Tdark GSG1 Germ cell-specific gene 1 protein

Protein Summary

Description

May cause the redistribution of PAPOLB from the cytosol to the endoplasmic reticulum.

Uniprot Accession IDs

• Q2KHT4
• Q8N4M3
• Q8NBR4
• Q8NBS0
• Q8NBT1
• Q96LP9
• Q96SI6
• Q9BUY4

Gene Name

• GSG1

Ensembl ID

• ENST00000337630
• ENSP00000336816
• ENSG00000111305
• ENST00000396302
• ENSP00000379596
• ENST00000432710
• ENSP00000405032
• ENST00000457134
• ENSP00000398384
• ENST00000537302
• ENSP00000441718

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.7
transcription factor	0.62
cellular component	0.6
PubMedID	0.56
cell type or tissue	0.54

Protein Classes

PANTHER Classes

Protein / Cytoskeletal Protein / Germ Cell-specific Gene 1 Protein

DTO Classes

Protein / Cellular Structure / Germ Cell-specific Gene 1 Protein

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.08   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 109   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.08   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 109   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0