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  4. Protein NKG7

Tdark Protein NKG7


 Comments

Property Summary

NCBI Gene PubMed Count 5
PubMed Score 9.72
PubTator Score 11.23

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Relevance (11)

Disease Z-score Confidence
Lethal midline granuloma 6 3.841 1.9
cutaneous lupus erythematosus 1,056
interstitial cystitis 2,299
lung adenocarcinoma 2,713
lung carcinoma 2,844
nephrosclerosis 329
non-small cell lung cancer 2,798
osteosarcoma 7,933
psoriasis 6,685
pulmonary arterial hypertension 36
tuberculosis 1,557

Expression

  Differential Expression (10)

Disease log2 FC p
nephrosclerosis 1.478 0.003
cutaneous lupus erythematosus 3.100 0.000
osteosarcoma -4.750 0.000
tuberculosis 1.100 0.001
non-small cell lung cancer -1.725 0.000
interstitial cystitis 1.500 0.004
lung adenocarcinoma -1.549 0.000
pulmonary arterial hypertension -1.300 0.021
lung carcinoma -1.300 0.000
psoriasis 1.200 0.000

Synonym

Accession Q16617
Symbols GIG1
GMP-17
p15-TIA-1

Gene

NKG7

PANTHER Protein Class (1)

 GO Component (1)

 Compartment GO Term (12)

Pathway (1)

 UniProt Keyword (7)

AA Sequence 

MELCRSLALLGGSLGLMFCLIALSTDFWFEAVGPTHSAHSGLWPTGHGDIISGYIHVTQTFSIMAVLWAL      1 - 70
VSVSFLVLSCFPSLFPPGHGPLVSTTAAFAAAISMVVAMAVYTSERWDQPPHPQIQTFFSWSFYLGWVSA     71 - 140
ILLLCTGALSLGAHCGGPRPGYETL                                                 141 - 165
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Text Mined References (6)

PMID Year Title
25416956 2014 A proteome-scale map of the human interactome network.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
8570616 1996 Characterization of GMP-17, a granule membrane protein that moves to the plasma membrane of natural killer cells following target cell recognition.
8458737 1993 Characterization of a novel gene (NKG7) on human chromosome 19 that is expressed in natural killer cells and T cells.
7510105 1994 Molecular cloning and characterization of G-CSF induced gene cDNA.