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Tbio
PRR4
Proline-rich protein 4

Protein Summary
Description
This gene encodes a member of the proline-rich protein family that lacks a conserved repetitive domain. This protein may play a role in protective functions in the eye. Alternative splicing result in multiple transcript variants. Read-through transcription also exists between this gene and the upstream PRH1 (proline-rich protein HaeIII subfamily 1) gene. [provided by RefSeq, Feb 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000228811
  • ENSP00000228811
  • ENSG00000111215
  • ENST00000544994
  • ENSP00000438046
  • ENST00000574424
  • ENSP00000459468
  • ENSG00000263247
  • ENST00000576999
  • ENSP00000461695
  • ENST00000614435
  • ENSP00000477689
  • ENSG00000282269
  • ENST00000632373
  • ENSP00000487830

Symbol
  • LPRP
  • PROL4
  • LPRP
  • PROL4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.77
interacting protein
0.61
tissue
0.57
cell line
0.53
small molecule perturbation
0.51


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 140.7   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 18   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 140.7   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 18   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0