Property Summary

NCBI Gene PubMed Count 20
PubMed Score 13.68
PubTator Score 8.38

Knowledge Summary

Patent

No data available

Expression

Synonym

Accession Q15041 B7Z6S5 B7Z791 F5GXP4 ARL-6-interacting protein 1
Symbols AIP1
ARMER
SPG61
ARL6IP

Gene

Gene RIF (4)

PMID Text
24076029 ARL6ip1 is a three-spanning transmembrane protein with a conophylline binding pocket.
20372863 ARL6IP1 may play a key role in cisplatin-induced apoptosis in CaSki cervical cancer cells by regulating the expression of apoptosis-associated proteins.
20213509 Down-regulation of ARL6IP1 expression arrested CaSki cell cycling at the G0/G1 phase and mitigated CaSki cell migration, determined by wound healing assays.
12754298 novel endoplasmic reticulum integral membrane protein which protects cells by inhibiting caspase-9 activity and reveal a possible role for ARMER in cell survival

AA Sequence

MAEGDNRSTNLLAAETASLEEQLQGWGEVMLMADKVLRWERAWFPPAIMGVVSLVFLIIYYLDPSVLSGV      1 - 70
SCFVMFLCLADYLVPILAPRIFGSNKWTTEQQQRFHEICSNLVKTRRRAVGWWKRLFTLKEEKPKMYFMT     71 - 140
MIVSLAAVAWVGQQVHNLLLTYLIVTSLLLLPGLNQHGIILKYIGMAKREINKLLKQKEKKNE           141 - 203
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Text Mined References (21)

PMID Year Title
25612671 2014 Identification and characterization of TMEM33 as a reticulon-binding protein.
25416956 2014 A proteome-scale map of the human interactome network.
24482476 2014 Exome sequencing links corticospinal motor neuron disease to common neurodegenerative disorders.
24262037 2014 Arl6IP1 has the ability to shape the mammalian ER membrane in a reticulon-like fashion.
24076029 2013 Determination of topological structure of ARL6ip1 in cells: identification of the essential binding region of ARL6ip1 for conophylline.
21516116 2011 Next-generation sequencing to generate interactome datasets.
20372863 2010 ARL6IP1 mediates cisplatin-induced apoptosis in CaSki cervical cancer cells.
20213509 2010 Inhibition of ADP-ribosylation factor-like 6 interacting protein 1 suppresses proliferation and reduces tumor cell invasion in CaSki human cervical cancer cells.
19946888 2010 Defining the membrane proteome of NK cells.
19060904 2009 An empirical framework for binary interactome mapping.
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