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Tbio
SLC17A1
Sodium-dependent phosphate transport protein 1

Protein Summary
Description
Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Plays a role in urate transport in the kidney (PubMed:27906618).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000244527
  • ENSP00000244527
  • ENSG00000124568
  • ENST00000468082
  • ENSP00000420546
  • ENST00000476801
  • ENSP00000420614

Symbol
  • NPT1
  • NPT1
  • NPT-1
  • NAPI-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.93
gene perturbation
0.9
co-expressed gene
0.85
phenotype
0.78
disease
0.63


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 84.81   (req: < 5)
Gene RIFs: 19   (req: <= 3)
Antibodies: 66   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 84.81   (req: >= 5)
Gene RIFs: 19   (req: > 3)
Antibodies: 66   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0