Tbio DIP2A Disco-interacting protein 2 homolog A

Protein Summary

Description

May provide positional cues for axon pathfinding and patterning in the central nervous system. The protein encoded by this gene may be involved in axon patterning in the central nervous system. This gene is not highly expressed. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Uniprot Accession IDs

• Q14689
• A6P4T3
• B4E0F0
• E7EMA5
• Q8IVA3
• Q8N4S2
• Q8TD89
• Q96ML9
• DIP2 homolog A

Gene Name

• DIP2A

Ensembl ID

• ENST00000400274
• ENSP00000383133
• ENSG00000160305
• ENST00000417564
• ENSP00000392066
• ENST00000435722
• ENSP00000415089
• ENST00000457905
• ENSP00000393434
• ENST00000466639
• ENSP00000430249

Symbol

• C21orf106
• DIP2
• KIAA0184
• DIP2
• C21orf106

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.84
histone modification site profile	0.82
microRNA	0.82
tissue sample	0.69
virus perturbation	0.68

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.01   (req: < 5)

Gene RIFs: 6   (req: <= 3)

Antibodies: 143   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.01   (req: >= 5)

Gene RIFs: 6   (req: > 3)

Antibodies: 143   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0