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Tbio
BOP1
Ribosome biogenesis protein BOP1

Protein Summary
Description
Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000569669
  • ENSP00000455106
  • ENSG00000261236
  • ENST00000642409
  • ENSP00000495401
  • ENSG00000285301

Symbol
  • KIAA0124
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
kinase perturbation
0.84
histone modification site profile
0.75
small molecule perturbation
0.69
tissue
0.67


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 39.05   (req: < 5)
Gene RIFs: 12   (req: <= 3)
Antibodies: 129   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 39.05   (req: >= 5)
Gene RIFs: 12   (req: > 3)
Antibodies: 129   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0