Property Summary

NCBI Gene PubMed Count 20
PubMed Score 21.88
PubTator Score 14.58

Knowledge Summary


No data available


  Disease Sources (5)

Disease Target Count
Alzheimer's disease 644
Disease Target Count P-value
ependymoma 2514 1.9627231299011E-20
atypical teratoid/rhabdoid tumor 1095 5.32333073575814E-10
ovarian cancer 8492 8.84297396781071E-10
pilocytic astrocytoma 3086 8.52941118580782E-9
oligodendroglioma 2849 2.69731765079199E-7
pediatric high grade glioma 2712 5.52133033842444E-7
sonic hedgehog group medulloblastoma 1482 6.25684186633751E-6
glioblastoma 5572 1.12433056246196E-5
medulloblastoma, large-cell 6234 1.5018534309033E-4
primitive neuroectodermal tumor 3031 3.01244826753796E-4
subependymal giant cell astrocytoma 2287 0.00191440964109195
non primary Sjogren syndrome sicca 840 0.0197957289113717
active ulcerative colitis 477 0.023991174019013
Down syndrome 548 0.0249602332145218
active Crohn's disease 918 0.029952310427311
astrocytic glioma 2241 0.0397997650922853
Disease Target Count Z-score Confidence
Substance abuse 55 3.515 1.8
Schizophrenia 503 3.055 1.5



Accession Q13875 A8K2C2 G5E945 Q13874 Q6DHZ6 Q8TBJ1


  Ortholog (3)

Species Source
Macaque OMA Inparanoid
Mouse OMA Inparanoid
Rat OMA Inparanoid

Gene RIF (6)

26077951 rs1768208 is associated with corticobasal degeneration.
24994843 The rs1768208 risk polymorphism in MOBP has prognostic value in behavioral-variant frontotemporal dementia.
23116876 Genotypes at MOBP and EIF2AK3 confer risk predominantly in APOE epsilon4-positive subjects, with indications of an interaction between APOE and MOBP or EIF2AK3 on Alzheimer's disease risk.
20877624 Observational study of gene-disease association. (HuGE Navigator)
17964117 MOBP mRNA levels were increased in the DLPFC white matter in patients with a history of substance abuse.
15009677 Decreased expression of a number of myelin-related genes, including myelin basic protein (MBP), proteolipid protein (PLP), and myelin-associated oligodendrocyte basic protein (MOBP) was noted in nucleus accumbens of cocaine abusers

AA Sequence


Text Mined References (21)

PMID Year Title
26871637 2016 Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
26077951 2015 Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy.
25416956 2014 A proteome-scale map of the human interactome network.
24994843 2014 Myelin oligodendrocyte basic protein and prognosis in behavioral-variant frontotemporal dementia.
23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
23116876 2013 An exploratory study on STX6, MOBP, MAPT, and EIF2AK3 and late-onset Alzheimer's disease.
21685912 2011 Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy.
20877624 2010 Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
19734545 2009 A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.
18839057 2008 Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies.