Property Summary

NCBI Gene PubMed Count 952
Grant Count 3,079
R01 Count 1,994
Funding $387,898,381.99
PubMed Score 3417.40
PubTator Score 1885.93

Knowledge Summary

Patent (143,944)

TINX Plot

  Disease Relevance (55)

Disease Z-score Confidence
Ataxia telangiectasia 31 8.286 4.0
Cancer 2,346 6.36 3.2
Nijmegen breakage syndrome 23 5.974 3.0
Telangiectasis 20 4.854 2.4
Cerebellar Ataxia 72 4.486 2.2
Fanconi's anemia 50 4.104 2.1
Seckel syndrome 34 3.715 1.9
Bloom syndrome 30 3.507 1.8
Werner syndrome 29 3.187 1.6
Microcephaly 149 3.124 1.6
Adenoid Cystic Carcinoma 99
Ataxia-Telangiectasia Variant 1
Bladder Neoplasm 109
Breast Cancer, Familial 12
Breast cancer 3,094 5.0
Carcinoma 2,147 1.0
Cardiomyopathy, Dilated 47
Cataract 104
Chronic Lymphocytic Leukemia 242
Fibrosis 40
Immune system cancer 38 1.0
Kidney cancer 118 1.0
Liver carcinoma 217
Lymphoid leukemia 69 1.0
Lymphoma, T-Cell, Cutaneous 21
Malignant lymphoma, lymphocytic, interme... 12 
Mammary Neoplasms 410
Melanoma 261 2.0
Multiple Sclerosis 498
Myocardial Infarction 126
Neoplastic Syndromes, Hereditary 48
Neurodegenerative disease 383 4.0
Pancreatic Neoplasm 79
Peripheral Neuropathy 303
Peripheral T-cell lymphoma 24
Pick disease 1,893
Prenatal Exposure Delayed Effects 9
Prostatic Neoplasms 471
Stomach Neoplasms 282
T-Cell Prolymphocytic Leukemia 1
Ventricular Dysfunction, Left 15
acute quadriplegic myopathy 1,157
astrocytic glioma 2,241
atypical teratoid/rhabdoid tumor 1,095
diabetes mellitus 1,663
ependymoma 2,514
malignant mesothelioma 3,162
medulloblastoma, large-cell 6,234
non primary Sjogren syndrome sicca 840
oligodendroglioma 2,849
osteosarcoma 7,933
ovarian cancer 8,484
progressive supranuclear palsy 674
sonic hedgehog group medulloblastoma 1,482
ulcerative colitis 2,087

Expression

  Differential Expression (16)

Disease log2 FC p
malignant mesothelioma 2.100 0.000
astrocytic glioma 1.500 0.014
ependymoma 1.600 0.006
oligodendroglioma 1.300 0.038
osteosarcoma 3.715 0.000
sonic hedgehog group medulloblastoma 1.800 0.000
atypical teratoid/rhabdoid tumor 1.500 0.000
medulloblastoma, large-cell 1.700 0.000
acute quadriplegic myopathy 1.030 0.000
diabetes mellitus -1.100 0.004
Multiple Sclerosis -1.400 0.000
non primary Sjogren syndrome sicca -1.200 0.019
Pick disease 1.200 0.000
progressive supranuclear palsy -1.300 0.009
ulcerative colitis 1.400 0.000
ovarian cancer -1.800 0.000

Synonym

Accession Q13315 B2RNX5 O15429 Q12758 Q16551 Q93007 Q9NP02 Q9UCX7
Symbols AT1
ATA
ATC
ATD
ATE
ATDC
TEL1
TELO1

Gene

ATM