SRSF11
Serine/arginine-rich splicing factor 11
Protein Summary
May function in pre-mRNA splicing. This gene encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors. Although the function of this protein is not yet known, structure and immunolocalization data suggest that it may play a role in pre-mRNA processing. Alternative splicing results in multiple transcript variants encoding different proteins. In addition, a pseudogene of this gene has been found on chromosome 12.[provided by RefSeq, Sep 2010]
- ENST00000370950
- ENSP00000359988
- ENSG00000116754
- ENST00000370951
- ENSP00000359989
- SFRS11
- p54
- NET2
- SFRS11
- dJ677H15.2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
interacting protein | 0.99 | ||
drug perturbation | 0.96 | ||
histone modification site profile | 0.86 | ||
ligand (protein) perturbation | 0.83 | ||
transcription factor perturbation | 0.8 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 7.99 (req: < 5)
Gene RIFs: 6 (req: <= 3)
Antibodies: 136 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 7.99 (req: >= 5)
Gene RIFs: 6 (req: > 3)
Antibodies: 136 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 7
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0