Tbio CDC42EP1 Cdc42 effector protein 1

Protein Summary

Description

Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts. CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin cytoskeleton reorganization at the plasma membrane. This protein is secreted and is primarily found in bone marrow. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q00587
• A8K825
• Q96GN1

Gene Name

• CDC42EP1

Ensembl ID

• ENST00000249014
• ENSP00000249014
• ENSG00000128283

Symbol

• BORG5
• CEP1
• MSE55
• CEP1
• BORG5
• MSE55

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
interacting protein	0.9
PubMedID	0.86
transcription factor binding site profile	0.86
ligand (protein) perturbation	0.83
virus perturbation	0.79

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.27   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 119   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.27   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 119   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0