PURG
Purine-rich element-binding protein gamma
Protein Summary
The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PUR, and has been implicated in the control of both DNA replication and transcription. This gene lies in close proximity to the Werner syndrome gene, but on the opposite strand, on chromosome 8p11. [provided by RefSeq, Apr 2016]
- ENST00000339382
- ENSP00000345168
- ENSG00000172733
- ENST00000475541
- ENSP00000418721
- PURGA
- PURGB
- PURG-A
- PURG-B
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
virus perturbation | 0.96 | ||
histone modification site profile | 0.87 | ||
kinase perturbation | 0.66 | ||
transcription factor | 0.66 | ||
transcription factor perturbation | 0.61 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 15.68 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 89 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 15.68 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 89 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 7
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0