Tbio PSKH1 Serine/threonine-protein kinase H1

Protein Summary

Description

May be a SFC-associated serine kinase (splicing factor compartment-associated serine kinase) with a role in intranuclear SR protein (non-snRNP splicing factors containing a serine/arginine-rich domain) trafficking and pre-mRNA processing.

Uniprot Accession IDs

• P11801
• Q9NY19

Gene Name

• PSKH1

Ensembl ID

• ENST00000291041
• ENSP00000291041
• ENSG00000159792

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.91
protein domain	0.85
tissue sample	0.7
histone modification site profile	0.63
cellular component	0.61

Protein Classes

DTO Classes

Protein / Kinase / Protein Kinase / Camk Group / Psk Family / Serine/threonine-protein Kinase H1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.71   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 123   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.71   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 123   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0