| Tbio | Protogenin |
May play a role in anteroposterior axis elongation.
This gene encodes a member of the immunoglobulin superfamily. The encoded transmembrane protein has been associated with the development of various tissues, especially neurogenesis. It has been suggested that this gene may be associated with attention deficit hyperactivity disorder (ADHD). [provided by RefSeq, Nov 2014]
This gene encodes a member of the immunoglobulin superfamily. The encoded transmembrane protein has been associated with the development of various tissues, especially neurogenesis. It has been suggested that this gene may be associated with attention deficit hyperactivity disorder (ADHD). [provided by RefSeq, Nov 2014]
Comments
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Liver Cirrhosis, Experimental | 769 | 0.0 | 0.0 |
| Disease | Target Count | P-value |
|---|---|---|
| non-small cell lung cancer | 2890 | 1.9e-15 |
| lung carcinoma | 2843 | 3.5e-10 |
| ovarian cancer | 8520 | 2.4e-06 |
| Breast cancer | 3578 | 6.0e-06 |
| group 3 medulloblastoma | 4104 | 2.5e-05 |
| cystic fibrosis | 1696 | 2.4e-04 |
| medulloblastoma, large-cell | 6241 | 4.5e-04 |
| Astrocytoma, Pilocytic | 3081 | 5.5e-04 |
| atypical teratoid / rhabdoid tumor | 5112 | 1.6e-03 |
| glioblastoma | 5792 | 5.9e-03 |
| primitive neuroectodermal tumor | 3035 | 6.3e-03 |
| oligodendroglioma | 2850 | 8.9e-03 |
| astrocytic glioma | 2597 | 1.9e-02 |
| pituitary cancer | 1972 | 2.7e-02 |
| osteosarcoma | 7950 | 2.8e-02 |
| subependymal giant cell astrocytoma | 2287 | 3.0e-02 |
| ependymoma | 4679 | 3.3e-02 |
| Disease | log2 FC | p |
|---|---|---|
| astrocytic glioma | 1.200 | 1.9e-02 |
| Astrocytoma, Pilocytic | 1.100 | 5.5e-04 |
| atypical teratoid / rhabdoid tumor | 2.400 | 1.6e-03 |
| Breast cancer | -1.100 | 6.0e-06 |
| cystic fibrosis | 1.027 | 2.4e-04 |
| ependymoma | 1.100 | 3.3e-02 |
| glioblastoma | 1.300 | 5.9e-03 |
| group 3 medulloblastoma | 3.000 | 2.5e-05 |
| lung carcinoma | -1.500 | 3.5e-10 |
| medulloblastoma, large-cell | 1.100 | 4.5e-04 |
| non-small cell lung cancer | -1.142 | 1.9e-15 |
| oligodendroglioma | 1.200 | 8.9e-03 |
| osteosarcoma | 1.547 | 2.8e-02 |
| ovarian cancer | -1.200 | 2.4e-06 |
| pituitary cancer | 1.300 | 2.7e-02 |
| primitive neuroectodermal tumor | 2.300 | 6.3e-03 |
| subependymal giant cell astrocytoma | 1.393 | 3.0e-02 |
| Species | Source | Disease |
|---|---|---|
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid EggNOG | ||
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| OMA EggNOG | ||
| Inparanoid OMA | ||
| Inparanoid OMA EggNOG |
MAPPLRPLARLRPPGMLLRALLLLLLLSPLPGVWCFSELSFVKEPQDVTVTRKDPVVLDCQAHGEVPIKV 1 - 70 TWLKNGAKMSENKRIEVLSNGSLYISEVEGRRGEQSDEGFYQCLAMNKYGAILSQKAHLALSTISAFEVQ 71 - 140 PISTEVHEGGVARFACKISSHPPAVITWEFNRTTLPMTMDRITALPTGVLQIYDVSQRDSGNYRCIAATV 141 - 210 AHRRKSMEASLTVIPAKESKSFHTPTIIAGPQNITTSLHQTVVLECMATGNPKPIISWSRLDHKSIDVFN 211 - 280 TRVLGNGNLMISDVRLQHAGVYVCRATTPGTRNFTVAMATLTVLAPPSFVEWPESLTRPRAGTARFVCQA 281 - 350 EGIPSPKMSWLKNGRKIHSNGRIKMYNSKLVINQIIPEDDAIYQCMAENSQGSILSRARLTVVMSEDRPS 351 - 420 APYNVHAETMSSSAILLAWERPLYNSDKVIAYSVHYMKAEGLNNEEYQVVIGNDTTHYIIDDLEPASNYT 421 - 490 FYIVAYMPMGASQMSDHVTQNTLEDVPLRPPEISLTSRSPTDILISWLPIPAKYRRGQVVLYRLSFRLST 491 - 560 ENSIQVLELPGTTHEYLLEGLKPDSVYLVRITAATRVGLGESSVWTSHRTPKATSVKAPKSPELHLEPLN 561 - 630 CTTISVRWQQDVEDTAAIQGYKLYYKEEGQQENGPIFLDTKDLLYTLSGLDPRRKYHVRLLAYNNIDDGY 631 - 700 QADQTVSTPGCVSVRDRMVPPPPPPHHLYAKANTSSSIFLHWRRPAFTAAQIINYTIRCNPVGLQNASLV 701 - 770 LYLQTSETHMLVQGLEPNTKYEFAVRLHVDQLSSPWSPVVYHSTLPEAPAGPPVGVKVTLIEDDTALVSW 771 - 840 KPPDGPETVVTRYTILYASRKAWIAGEWQVLHREGAITMALLENLVAGNVYIVKISASNEVGEGPFSNSV 841 - 910 ELAVLPKETSESNQRPKRLDSADAKVYSGYYHLDQKSMTGIAVGVGIALTCILICVLILIYRSKARKSSA 911 - 980 SKTAQNGTQQLPRTSASLASGNEVGKNLEGAVGNEESLMPMIMPNSFIDAKGGTDLIINSYGPIIKNNSK 981 - 1050 KKWFFFQDSKKIQVEQPQRRFTPAVCFYQPGTTVLISDEDSPSSPGQTTSFSRPFGVAADTEHSANSEGS 1051 - 1120 HETGDSGRFSHESNDEIHLSSVISTTPPNL 1121 - 1150 //
