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Tdark Serine protease 55

Probable serine protease.

This gene encodes a member of a group of membrane-anchored chymotrypsin (S1)-like serine proteases. The enocoded protein is primarily expressed in the Leydig and Sertoli cells of the testis and may be involved in male fertility. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]

 Comments

Property Summary

NCBI Gene PubMed Count 5
PubMed Score 3.86
PubTator Score 5.92

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (2)

Disease Target Count Z-score Confidence
Carcinoma 11493 0.0 0.7
Disease Target Count Z-score Confidence
Alzheimer's disease 658 0.0 1.2
Breast cancer 3578 0.0 1.0

Expression

Synonym

Accession Q6UWB4 E5RJX5
Symbols TSP1
CT153
T-SP1
UNQ9391

Gene

PRSS55

PANTHER Protein Class (3)

  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG

 UniProt Keyword (14)

See all...

 GO Function (1)

 GO Component (2)

 Compartment GO Term (12)

 GWAS Trait (1)

 HCA RNA Cell Line (6)

Gene RIF (1)

AA Sequence 

MLLFSVLLLLSLVTGTQLGPRTPLPEAGVAILGRARGAHRPQPPHPPSPVSECGDRSIFEGRTRYSRITG      1 - 70
GMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGTNDLTSPSMEIKEVA     71 - 140
SIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQPGPATWRECWVAGWGQTNAADKNSVKTDLM    141 - 210
KAPMVIMDWEECSKMFPKLTKNMLCAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKN    211 - 280
TPGIYTSLVNYNLWIEKVTQLEGRPFNAEKRRTSVKQKPMGSPVSGVPEPGSPRSWLLLCPLSHVLFRAI    281 - 350
LY                                                                        351 - 352
//

Text Mined References (7)

PMID Year Title