Tdark PRDM7 Probable histone-lysine N-methyltransferase PRDM7

Protein Summary

Description

Probable histone methyltransferase. This gene encodes a member of a family of proteins that may have roles in transcription and other nuclear processes. The encoded protein contains a KRAB (Kruppel-associated box) domain -A box and a SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain and may function as a histone methyltransferase. [provided by RefSeq, Aug 2013]

Uniprot Accession IDs

• Q9NQW5
• A4Q9G8
• Q08EM4
• Q9NQW4

Gene Name

• PRDM7

Ensembl ID

• ENST00000449207
• ENSP00000396732
• ENSG00000126856
• ENST00000643008
• ENSP00000496449

Symbol

• PFM4
• PFM4
• ZNF910

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.6
protein domain	0.58
tissue	0.54
cell line	0.47
microRNA	0.47

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.43   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 53   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.43   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 53   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0