Property Summary

NCBI Gene PubMed Count 10
PubMed Score 5.94
PubTator Score 193.32

Knowledge Summary


No data available


  Disease (1)

Disease Target Count P-value
psoriasis 6685 5.7e-12
ulcerative colitis 2087 1.1e-04
active Crohn's disease 918 1.4e-03


  Differential Expression (3)

Disease log2 FC p
active Crohn's disease -2.651 1.4e-03
ulcerative colitis -2.900 1.1e-04
psoriasis -1.400 5.7e-12


Accession Q96NZ9 B7ZL57 B7ZL58 E9KL31 Q5VWY4 Q7Z4X5 Q8IWR3 Q8NCS2
Symbols UPA


  Ortholog (1)

Species Source Disease
Macaque EggNOG Inparanoid

Gene RIF (2)

24374861 PRAP1 is a protein interacting partner of MAD1 and that PRAP1 is able to down-regulate MAD1 and suppress mitotic checkpoint signalling in hepatocellular carcinoma.
23235459 Induction of PRAP1 expression by p53 in response to DNA-damaging agents contributes to cancer cell survival.

AA Sequence

EEDQDHIYHPQ                                                               141 - 151

Text Mined References (12)

PMID Year Title
25416956 2014 A proteome-scale map of the human interactome network.
24374861 2014 Proline-rich acidic protein 1 (PRAP1) is a novel interacting partner of MAD1 and has a suppressive role in mitotic checkpoint signalling in hepatocellular carcinoma.
23235459 2012 PRAP1 is a novel executor of p53-dependent mechanisms in cell survival after DNA damage.
20736409 2010 Systematic mapping and functional analysis of a family of human epididymal secretory sperm-located proteins.
20674898 2010 Uterine luminal epithelium-specific proline-rich acidic protein 1 (PRAP1) as a marker for successful embryo implantation.
17207965 2007 hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15164054 2004 The DNA sequence and comparative analysis of human chromosome 10.
14583459 2003 The proline-rich acidic protein is epigenetically regulated and inhibits growth of cancer cell lines.
12975309 2003 The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
9065197 1997 A novel complementary deoxyribonucleic acid is abundantly and specifically expressed in the uterus during pregnancy.