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Tbio PRA1 family protein 2

May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis.

 Comments

Property Summary

NCBI Gene PubMed Count 11
PubMed Score 15.49
PubTator Score 9.49

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (3)

Disease Target Count Z-score Confidence
Liver Cirrhosis, Experimental 769 0.0 0.0
Disease Target Count P-value
ovarian cancer 8520 8.0e-05
group 3 medulloblastoma 4104 3.5e-03
Disease Target Count Z-score Confidence
Neuroblastoma 80 3.29 1.6

Expression

  Differential Expression (2)

Disease log2 FC p
group 3 medulloblastoma -1.200 3.5e-03
ovarian cancer 1.100 8.0e-05

Synonym

Accession O60831 B2RD20
Symbols JM4
Yip6a

Gene

PRAF2

PANTHER Protein Class (2)

  Ortholog (4)

Species Source Disease
Inparanoid OMA
Inparanoid OMA
Inparanoid OMA
Inparanoid OMA

 UniProt Keyword (9)

 GO Component (2)

 GO Process (2)

 Compartment GO Term (29)

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 MGI Phenotype (1)

 HCA RNA Cell Line (56)

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Gene RIF (8)

AA Sequence 

MSEVRLPPLRALDDFVLGSARLAAPDPCDPQRWCHRVINNLLYYQTNYLLCFGIGLALAGYVRPLHTLLS      1 - 70
ALVVAVALGVLVWAAETRAAVRRCRRSHPAACLAAVLAVGLLVLWVAGGACTFLFSIAGPVLLILVHASL     71 - 140
RLRNLKNKIENKIESIGLKRTPMGLLLEALGQEQEAGS                                    141 - 178
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Text Mined References (13)

PMID Year Title