| Tdark | Protein phosphatase 1 regulatory subunit 36 |
Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.
Comments
| Disease | Target Count | P-value |
|---|---|---|
| lung carcinoma | 2843 | 5.7e-18 |
| nasopharyngeal carcinoma | 1058 | 6.9e-08 |
| posterior fossa group B ependymoma | 416 | 3.5e-07 |
| pituitary cancer | 1972 | 1.4e-04 |
| subependymal giant cell astrocytoma | 2287 | 3.0e-02 |
| Disease | log2 FC | p |
|---|---|---|
| lung carcinoma | 1.600 | 5.7e-18 |
| nasopharyngeal carcinoma | -1.100 | 6.9e-08 |
| pituitary cancer | 1.200 | 1.4e-04 |
| posterior fossa group B ependymoma | 2.000 | 3.5e-07 |
| subependymal giant cell astrocytoma | 1.142 | 3.0e-02 |
MYRVPEFYARRKRLGGQTPYLMDQLGLRLGMWYWKDETRTLEFRRFAAEDSVQWLLKHHPHFTPAAEVKE 1 - 70 KGKKGKAVHFAETDGPASDRLTDKRLAAKDDKSAKAVEKRGQQGTITLDDVKFVTLLLLQDTEMQRICSF 71 - 140 TTFMRNKNLDNFLMALLYYLSHYLEKNSLEKKPKSYMVGLVEKKEMELVLSELEAAQRYLAQKYCILVLG 141 - 210 LAVPDKHHMCCGKEKISDTQKDWKFFESFYTFCTYVAWIVFRRQHLTEIEEEVGRLFRTNMFNIPRRRRE 211 - 280 DEESGGEKKRMTFVQFRRMMAKRPAIKKAINMRSPVMSTLLPSLREKAQNVFEKKYHQVDVRFPAEMQKH 281 - 350 VGTLDSVPMPVVGILGEPRCLFNPHTLHPLDPEENTKSFGRYPSLMENNNMRIQDTLDLVMKTLSSHTSC 351 - 420 PK 421 - 422 //
