Tdark PPIAL4A Peptidyl-prolyl cis-trans isomerase A-like 4A

Protein Summary

Description

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

Uniprot Accession IDs

• Q9Y536
• PPIase A-like 4A

Gene Name

• PPIAL4A

Ensembl ID

• ENST00000577856
• ENSP00000485206
• ENSG00000263353

Symbol

• COAS2
• PPIAL4B
• COAS2
• COAS-2
• PPIAL4
• PPIAL4B

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell type or tissue	0.93
tissue	0.59
protein domain	0.58
cell line	0.57
protein complex	0.4

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.73   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 35   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.73   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 35   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0