| Tbio | POU domain, class 3, transcription factor 1 |
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Thought to be involved in early embryogenesis and neurogenesis.
Comments
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Arthritis, Rheumatoid | 174 | 0.0 | 0.0 |
| Disease | Target Count |
|---|---|
| Major Depressive Disorder | 301 |
| Rheumatoid arthritis | 1191 |
| Unipolar Depression | 250 |
| Disease | Target Count | P-value |
|---|---|---|
| posterior fossa group A ependymoma | 468 | 1.2e-08 |
| ovarian cancer | 8520 | 2.9e-08 |
| psoriasis | 6694 | 2.1e-05 |
| group 4 medulloblastoma | 1855 | 1.6e-04 |
| medulloblastoma, large-cell | 6241 | 1.6e-03 |
| cutaneous lupus erythematosus | 1057 | 8.0e-03 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Bipolar Disorder | 666 | 3.792 | 1.9 |
| Neurogenic bowel | 6 | 3.755 | 1.9 |
| Schizophreniform disorder | 5 | 3.205 | 1.6 |
| Disease | log2 FC | p |
|---|---|---|
| cutaneous lupus erythematosus | -1.400 | 8.0e-03 |
| group 4 medulloblastoma | -1.200 | 1.6e-04 |
| medulloblastoma, large-cell | 1.200 | 1.6e-03 |
| ovarian cancer | 1.300 | 2.9e-08 |
| posterior fossa group A ependymoma | -1.100 | 1.2e-08 |
| psoriasis | 2.500 | 2.1e-05 |
MATTAQYLPRGPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGAGAGHPVGLAH 1 - 70 PQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQGAAHAGAAWAQGSTAHHLGPA 71 - 140 MSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGA 141 - 210 HGHAHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLAL 211 - 280 GTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEVGV 281 - 350 KGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPG 351 - 420 GGGASPPSAPPPPPPAALHHHHHHTLPGSVQ 421 - 451 //
