Property Summary

NCBI Gene PubMed Count 13
PubMed Score 13.33
PubTator Score 12.68

Knowledge Summary


No data available


  Disease (1)

Disease Target Count P-value
tuberculosis 1563 4.8e-06
ovarian cancer 8491 4.1e-05
osteosarcoma 7933 5.3e-04
glioblastoma 5572 8.6e-04
group 3 medulloblastoma 2254 1.3e-03
lung cancer 4473 2.7e-03


  Differential Expression (6)

Disease log2 FC p
osteosarcoma -1.403 5.3e-04
glioblastoma 1.300 8.6e-04
tuberculosis 1.400 4.8e-06
lung cancer 1.600 2.7e-03
group 3 medulloblastoma 1.200 1.3e-03
ovarian cancer 1.800 4.1e-05


Accession Q969H6 A6NL80 Q53FS5 Q9Y2Q6 hPop5
Symbols RPP2


  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG

Gene RIF (3)

25704799 archaeal homologs of the human RNase P proteins Pop5 and Rpp30
22082156 Knockdown of processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae; POP5) by siRNA enhances the early stages of HIV-1 replication in HeLa-CD4 cells infected with viral pseudotypes HIV89.6R and HIV8.2N
18164267 Molecular mechanism by which Cartilage-hair hypolasia-associated mutations affect the function of RNase MRP.

AA Sequence

SVTRSCLLEEEEESGEEAAEAME                                                   141 - 163

Text Mined References (20)

PMID Year Title
25704799 2015 On archaeal homologs of the human RNase P proteins Pop5 and Rpp30 in the hyperthermophilic archaeon Thermococcus kodakarensis.
25416956 2014 A proteome-scale map of the human interactome network.
22458338 2012 Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses.
21406692 2011 System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
21269460 2011 Initial characterization of the human central proteome.
19413330 2009 Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
18691976 2008 Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
18669648 2008 A quantitative atlas of mitotic phosphorylation.
18164267 2008 Cartilage-hair hypoplasia-associated mutations in the RNase MRP P3 domain affect RNA folding and ribonucleoprotein assembly.
17081983 2006 Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
16541075 2006 The finished DNA sequence of human chromosome 12.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15096576 2004 Mutual interactions between subunits of the human RNase MRP ribonucleoprotein complex.
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
11413139 2001 hPop5, a protein subunit of the human RNase MRP and RNase P endoribonucleases.
11042152 2000 Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.
10931946 2000 Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.
10352175 1999 hPop4: a new protein subunit of the human RNase MRP and RNase P ribonucleoprotein complexes.
8125298 1994 Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.