Property Summary

NCBI Gene PubMed Count 10
PubMed Score 56.95
PubTator Score 12.64

Knowledge Summary


No data available


  Disease (3)


  Differential Expression (6)

Disease log2 FC p
Down syndrome 1.100 1.3e-03
Multiple myeloma 1.741 1.9e-03
osteosarcoma 1.221 1.1e-02
primary pancreatic ductal adenocarcinoma -1.258 4.9e-03
lung cancer 1.200 2.6e-02
pancreatic cancer -1.300 2.6e-03

Protein-protein Interaction (6)

Gene RIF (2)

20379614 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
11331941 Results in mouse suggest that this is the only gene from the Down Syndrome Critical Region expressed in the developing tongue and that the encoded protein may be involved in pathophysiology of tongue malformation seen in Down syndrome.

AA Sequence

SEVNQMFFLAAKELYTKN                                                        141 - 158

Text Mined References (12)

PMID Year Title
20379614 Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
19054851 2008 Human protein factory for converting the transcriptome into an in vitro-expressed proteome,.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15221505 2004 Protein levels of genes encoded on chromosome 21 in fetal Down Syndrome brain (Part V): overexpression of phosphatidyl-inositol-glycan class P protein (DSCR5).
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
11331941 2001 Molecular cloning and characterization of a gene expressed in mouse developing tongue, mDscr5 gene, a homolog of human DSCR5 (Down syndrome Critical Region gene 5).
11102867 2000 Dissecting and manipulating the pathway for glycosylphos-phatidylinositol-anchor biosynthesis.
10944123 2000 Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2.
10907851 2000 A novel gene, DSCR5, from the distal Down syndrome critical region on chromosome 21q22.2.
10830953 2000 The DNA sequence of human chromosome 21.
10814524 2000 Isolation of two novel genes, DSCR5 and DSCR6, from Down syndrome critical region on human chromosome 21q22.2.