Property Summary

NCBI Gene PubMed Count 9
PubMed Score 6.96
PubTator Score 5.87

Knowledge Summary


No data available


  Disease (2)

Disease Target Count
Liver neoplasms 108
Disease Target Count P-value
adrenocortical carcinoma 1427 5.0e-04
acute myeloid leukemia 785 4.5e-02


  Differential Expression (2)

Disease log2 FC p
adrenocortical carcinoma 1.096 5.0e-04
acute myeloid leukemia 1.200 4.5e-02


Accession Q9NUG6 B2R511 Q96GP3 Q9BUW8
Symbols PDRG


  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG

Gene RIF (4)

25706919 PDRG1 was significantly increased in tumors low of miR-214.
21193842 PDRG1 expression is increased in multiple human malignancies suggesting it to be a high-value novel tumor marker that could play a role in cancer development and/or progression.
19450687 Is part of an RNA polymerase II-associated complex with possible chaperone activity.
14562055 Cloning and characterization of a novel gene PDRG that is differentially regulated by p53 and ultraviolet radiation

AA Sequence


Text Mined References (11)

PMID Year Title
25706919 2015 MicroRNA-214 suppresses oncogenesis and exerts impact on prognosis by targeting PDRG1 in bladder cancer.
22814378 2012 N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
21193842 2011 PDRG1, a novel tumor marker for multiple malignancies that is selectively regulated by genotoxic stress.
19450687 2009 High-resolution mapping of the protein interaction network for the human transcription machinery and affinity purification of RNA polymerase II-associated complexes.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14743216 2004 A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
14562055 2003 Cloning and characterization of a novel gene PDRG that is differentially regulated by p53 and ultraviolet radiation.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
11780052 2001 The DNA sequence and comparative analysis of human chromosome 20.
8889548 1996 Normalization and subtraction: two approaches to facilitate gene discovery.