Tbio PARD3B Partitioning defective 3 homolog B

Protein Summary

Description

Putative adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions.

Uniprot Accession IDs

• Q8TEW8
• E9PE87
• Q8IUC7
• Q8IUC9
• Q96DK9
• Q96N09
• Q96NX6
• Q96NX7
• Q96Q29

Gene Name

• PARD3B

Ensembl ID

• ENST00000349953
• ENSP00000340280
• ENSG00000116117
• ENST00000351153
• ENSP00000317261
• ENST00000358768
• ENSP00000351618
• ENST00000406610
• ENSP00000385848
• ENST00000415947
• ENSP00000407718

Symbol

• ALS2CR19
• PAR3B
• PAR3L
• PAR3B
• PAR3L
• ALS2CR19
• PAR3beta

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
trait	0.99
histone modification site profile	0.82
kinase perturbation	0.81
phenotype	0.81
cell line	0.69

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.86   (req: < 5)

Gene RIFs: 10   (req: <= 3)

Antibodies: 36   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.86   (req: >= 5)

Gene RIFs: 10   (req: > 3)

Antibodies: 36   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0