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Tbio
HMGN5
High mobility group nucleosome-binding domain-containing protein 5

Protein Summary
Description
Preferentially binds to euchromatin and modulates cellular transcription by counteracting linker histone-mediated chromatin compaction. This gene encodes a nuclear protein with similarities to the high mobility group proteins, HMG14 and HMG17, which suggests that this protein may function as a nucleosomal binding and transcriptional activating protein. [provided by RefSeq, Sep 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000358130
  • ENSP00000350848
  • ENSG00000198157

Symbol
  • NSBP1
  • NSBP1
  • NBP-45
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.73
transcription factor perturbation
0.68
tissue sample
0.64
biological process
0.63
cell type or tissue
0.63


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 47.76   (req: < 5)
Gene RIFs: 30   (req: <= 3)
Antibodies: 127   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 47.76   (req: >= 5)
Gene RIFs: 30   (req: > 3)
Antibodies: 127   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0