Property Summary

NCBI Gene PubMed Count 19
PubMed Score 4.53
PubTator Score 1.33

Knowledge Summary


No data available


  Disease Sources (1)

Disease Target Count P-value
oligodendroglioma 2849 5.38412238426802E-20
posterior fossa group B ependymoma 1530 5.20269539520574E-17
group 3 medulloblastoma 2254 2.77059050450717E-8
pediatric high grade glioma 2712 4.10740082199171E-8
medulloblastoma, large-cell 6234 1.01359858400774E-7
atypical teratoid / rhabdoid tumor 4369 2.87300775767622E-6
pilocytic astrocytoma 3086 3.38951621546851E-6
glioblastoma 5572 8.61049183014506E-6
astrocytic glioma 2241 0.00235119804379792
Pick disease 1893 0.00994946017649999
subependymal giant cell astrocytoma 2287 0.0197805184693632
primitive neuroectodermal tumor 3031 0.032402566696737


  Differential Expression (12)


Accession P63215 B2R4S7 P29798 Q61014


  Ortholog (9)

Gene RIF (3)

23326349 Findings suggest a wide-ranging mechanism by which direct interaction of Gbetagamma with specific chromatin bound transcription factors regulates functional gene networks in response to GPCR activation in cells including the angiotensin II type 1 receptor.
22082156 Knockdown of guanine nucleotide binding protein (G protein), gamma 3 (GNG3) by siRNA enhances the early stages of HIV-1 replication in HeLa-CD4 cells infected with viral pseudotypes HIV89.6R and HIV8.2N
20534534 Golgi structure and secretion is regulated by receptor-induced G protein betagamma complex translocation

AA Sequence

FCALL                                                                      71 - 75

Text Mined References (20)

PMID Year Title
26900580 2016 Pathogenic mechanism of recurrent mutations of SCN8A in epileptic encephalopathy.
23326349 2013 Interaction of G-protein ?? complex with chromatin modulates GPCR-dependent gene regulation.
20534534 2010 Regulation of Golgi structure and secretion by receptor-induced G protein ?? complex translocation.
17185339 2007 Evidence for association of GABA(B) receptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins.
16344560 2006 Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15314181 2004 Mice with deficiency of G protein gamma3 are lean and have seizures.
15078334 2004 Characterization of heterotrimeric G protein complexes in rice plasma membrane.
14702039 2004 Complete sequencing and characterization of 21,243 full-length human cDNAs.
12626323 2003 Glucagon and regulation of glucose metabolism.