Property Summary

NCBI Gene PubMed Count 34
PubMed Score 159.68
PubTator Score 158.50

Knowledge Summary


No data available


  Disease Sources (2)

Disease Target Count P-value
sonic hedgehog group medulloblastoma 1482 5.86703645814E-7
atypical teratoid / rhabdoid tumor 4369 4.86483679986927E-6
medulloblastoma, large-cell 6234 7.98819116872439E-6
glioblastoma 5572 1.56126358969132E-5
ovarian cancer 8492 2.03811691561546E-5
primitive neuroectodermal tumor 3031 2.88984478878622E-5
osteosarcoma 7933 6.73785959799966E-5
intraductal papillary-mucinous neoplasm (IPMN) 3289 9.1734935940852E-4
Multiple myeloma 1328 0.00439612077038022
Waldenstrons macroglobulinemia 765 0.0235309438431662
lung cancer 4473 0.024250832610903
Disease Target Count Z-score Confidence
Mesenchymal chondrosarcoma 4 3.688 1.8
Necrotizing fasciitis 9 3.102 1.6



Accession P62249 B2RDD5 P17008
Symbols S16



4UG0   4V6X   5AJ0   5A2Q   5FLX  

  Ortholog (15)

Gene RIF (6)

26362536 HIV-1 Gag interacts with RPL27AP6 as demonstrated by proximity dependent biotinylation proteomics
25893343 Report dysregulated expression of RPS16 in disc degeneration.
20198863 Results obtained support the possibility of the autoregulation of rpS13 pre-mRNA splicing through feedback mechanism.
19773262 Observational study of gene-disease association. (HuGE Navigator)
19559069 Data demonstrated that while ribosomal proteins S16 and S5 is able to bind to the 18S rRNA independently, their simultaneous binding has a noticeable synergetic effect.
18318121 RpS16 was shown to specifically bind to the transcript forming a stable complex with the apparent dissociation constant of (1.3 +/- 0.1) x 10(-8) M at 20 degrees C.

AA Sequence

YQKSYR                                                                    141 - 146

Text Mined References (37)

PMID Year Title
25944712 2015 N-terminome analysis of the human mitochondrial proteome.
25893343 2015 Dysregulated COL3A1 and RPL8, RPS16, and RPS23 in Disc Degeneration Revealed by Bioinformatics Methods.
24725412 2014 Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease.
23979707 2013 SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers.
23636399 2013 Structures of the human and Drosophila 80S ribosome.
22681889 2012 The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
21423176 2011 Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for ?-Pix in negative regulation of focal adhesion maturation.
21269460 2011 Initial characterization of the human central proteome.
20458337 MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
20198863 [Human ribosomal protein S16 inhibites excision of the first intron from its own].