Tbio | Glia maturation factor beta |
This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells.
Comments
Disease | Target Count | Z-score | Confidence |
---|---|---|---|
Multiple Sclerosis | 498 | 3.747 | 1.9 |
Disease | log2 FC | p |
---|---|---|
cutaneous lupus erythematosus | 1.200 | 0.007 |
psoriasis | 2.700 | 0.000 |
osteosarcoma | 2.415 | 0.001 |
atypical teratoid / rhabdoid tumor | 1.700 | 0.000 |
glioblastoma | 1.800 | 0.000 |
medulloblastoma | 1.400 | 0.000 |
medulloblastoma, large-cell | 1.700 | 0.001 |
primitive neuroectodermal tumor | 1.100 | 0.000 |
acute quadriplegic myopathy | 1.158 | 0.000 |
Atopic dermatitis | 1.100 | 0.000 |
tuberculosis and treatment for 3 months | -1.300 | 0.000 |
intraductal papillary-mucinous neoplasm ... | 1.500 | 0.042 |
lung cancer | 1.400 | 0.010 |
diabetes mellitus | -1.100 | 0.008 |
pediatric high grade glioma | 1.200 | 0.002 |
pilocytic astrocytoma | 1.200 | 0.001 |
aldosterone-producing adenoma | -1.140 | 0.024 |
breast carcinoma | 1.200 | 0.000 |
progressive supranuclear palsy | -1.100 | 0.032 |
ductal carcinoma in situ | 1.200 | 0.001 |
invasive ductal carcinoma | 1.900 | 0.000 |
ovarian cancer | -2.200 | 0.000 |
Down syndrome | 1.500 | 0.001 |
Species | Source |
---|---|
Chimp | OMA EggNOG |
Macaque | OMA EggNOG |
Mouse | OMA EggNOG Inparanoid |
Rat | OMA Inparanoid |
Dog | OMA Inparanoid |
Horse | OMA EggNOG Inparanoid |
Cow | OMA EggNOG Inparanoid |
Pig | OMA EggNOG Inparanoid |
Opossum | EggNOG Inparanoid |
Platypus | OMA EggNOG |
Chicken | OMA Inparanoid |
Anole lizard | OMA EggNOG Inparanoid |
Xenopus | OMA EggNOG Inparanoid |
Zebrafish | OMA EggNOG Inparanoid |
PMID | Text |
---|---|
22035352 | The distribution of GMF-immunoreactive cells in and around amyloid plaques and neurofibrillary tangles suggests involvement of GMF in inflammatory responses through reactive glia and a role of GMF in Alzheimer disease pathology. |
21835226 | GMF co-localizes with amyloid plaques and neurofibrillary tangles in Alzheimer brains, implicating significant upregulation of GMF expression under conditions of neurodegeneration. |
19086053 | Observational study of gene-disease association. (HuGE Navigator) |
18171522 | There is a significant increase in GMF beta protein expression levels in IFN beta-1a treated LX-2 cells. |
16115230 | GMFB promoted T-cell differentiation into CD4-/CD8+ cells when analysed by two-colour flow cytometry. |
PMID | Year | Title |
---|---|---|
24275569 | 2014 | An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. |
23259602 | 2012 | Genome-wide association scan of dental caries in the permanent dentition. |
22814378 | 2012 | N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. |
22223895 | 2012 | Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-?-acetylation features. |
22035352 | 2012 | Expression of glia maturation factor in neuropathological lesions of Alzheimer's disease. |
21835226 | 2011 | Augmented expression of glia maturation factor in Alzheimer's disease. |
21269460 | 2011 | Initial characterization of the human central proteome. |
20547056 | 2010 | Identification of glia maturation factor beta as an independent prognostic predictor for serous ovarian cancer. |
19413330 | 2009 | Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. |
19086053 | 2009 | Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. |
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