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Tbio Glia maturation factor beta

This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells.

 Comments

Property Summary

NCBI Gene PubMed Count 15
PubMed Score 181.11
PubTator Score 60.68

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (3)

Disease Target Count Z-score Confidence
Carcinoma 11493 0.0 0.5
Disease Target Count Z-score Confidence
Multiple Sclerosis 540 3.72 1.9

Expression

  Differential Expression (23)

Disease log2 FC p
acute quadriplegic myopathy 1.158 6.7e-07
aldosterone-producing adenoma -1.140 2.4e-02
Astrocytoma, Pilocytic 1.200 7.9e-04
Atopic dermatitis 1.100 2.3e-04
atypical teratoid / rhabdoid tumor 1.700 1.1e-06
breast carcinoma 1.200 8.5e-19
cutaneous lupus erythematosus 1.200 6.8e-03
diabetes mellitus -1.100 7.8e-03
Down syndrome 1.500 1.0e-03
ductal carcinoma in situ 1.200 6.9e-04
glioblastoma 1.800 1.5e-06
group 4 medulloblastoma 1.100 3.0e-02
intraductal papillary-mucinous neoplasm ... 1.500 4.2e-02
invasive ductal carcinoma 1.900 2.0e-04
lung cancer 1.400 1.0e-02
medulloblastoma, large-cell 1.700 1.1e-03
osteosarcoma 2.415 5.6e-04
ovarian cancer -2.200 1.9e-08
pediatric high grade glioma 1.200 2.4e-03
primitive neuroectodermal tumor 1.100 1.1e-04
progressive supranuclear palsy -1.100 3.2e-02
psoriasis 2.700 1.5e-04
tuberculosis -1.200 2.3e-05

Synonym

Accession P60983 B2R499 P17774 Q9BS35 GMF-beta
Symbols GMF

Gene

GMFB

PANTHER Protein Class (2)

  Ortholog (13)

Species Source Disease
Inparanoid OMA EggNOG
OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA
Inparanoid OMA
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid EggNOG
Inparanoid OMA
Inparanoid OMA EggNOG
Inparanoid OMA EggNOG

 UniProt Keyword (5)

 GO Function (6)

 GO Component (1)

 GO Process (6)

 Compartment GO Term (4)

 MGI Phenotype (2)

 GWAS Trait (1)

 HCA RNA Cell Line (56)

See all...

Protein-protein Interaction (8)

HSPA8   RAB3GAP1   ALAD   SPAG9   CARM1   ACADL   GMFG   TUBB8  

Gene RIF (5)

AA Sequence 

MSESLVVCDVAEDLVEKLRKFRFRKETNNAAIIMKIDKDKRLVVLDEELEGISPDELKDELPERQPRFIV      1 - 70
YSYKYQHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNKLVQTAELTKVFEIRNTEDLTEEWLREKLGF     71 - 140
FH                                                                        141 - 142
//

Text Mined References (22)

PMID Year Title