Property Summary

NCBI Gene PubMed Count 1,611
Grant Count 3,004
R01 Count 1,747
Funding $319,334,477.54
PubMed Score 4696.10
PubTator Score 3962.96

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Relevance (99)

Disease Z-score Confidence
Cowden disease 16 7.422 3.7
Cancer 2,346 7.174 3.6
Bannayan-Riley-Ruvalcaba syndrome 8 6.4 3.2
Proteus syndrome 6 4.676 2.3
Juvenile polyposis syndrome 7 4.427 2.2
Peutz-Jeghers syndrome 23 4.361 2.2
Autistic Disorder 320 3.965 2.0
Parkinson's disease 364 3.774 1.9
Lipomatosis 11 3.678 1.8
Endometriosis 535 3.596 1.8
Adenoma 165 3.292 1.6
Papilloma 27 3.154 1.6
diabetes mellitus 1,663 3.094 1.5
Vascular disease 281 3.033 1.5
Acute Megakaryocytic Leukemias 4
Adenocarcinoma 115
Adenoid Cystic Carcinoma 99
Anisometropia 16
Asthma 349
Breast cancer 3,094 2.0
Carcinoma 2,147 2.0
Chromosome 10q23 Deletion Syndrome 2
Craniofacial Abnormalities 147
DOID:2627 14 2.0
Dermatologic disorders 65
Developmental Disabilities 20
Disease Progression 125
Dysplastic gangliocytoma of cerebellum (... 1 
Endometrial Hyperplasia 5
Endometrial Neoplasms 50
Endometrial cancer 25 2.0
Endometrial carcinoma 18
Familial meningioma 5
GLIOMA SUSCEPTIBILITY 2 1
Glioma 65
Hamartoma Syndrome, Multiple 9
Head and neck squamous cell carcinoma 12 5.0
Hemangioma 35
Hereditary Breast and Ovarian Cancer Syn... 14 
Hypertensive disease 193
IGA Glomerulonephritis 454
Insulin Resistance 48
Intellectual disability 573
Kidney cancer 118 1.0
LEOPARD Syndrome 20
Language Development Disorders 9
Leukemia 88
Lhermitte-Duclos disease 1
Lipoma 19
Long QT syndrome 52
Lung Neoplasms 171
Lymphoma 56
MACROCEPHALY/AUTISM SYNDROME 1
MELANOMA, CUTANEOUS MALIGNANT, 1 4
Malignant neoplasm of prostate 67
Mammary Neoplasms 410
Mediastinal Germ Cell Tumor 2
Melanoma 261 1.0
Meningioma 26
Motor Skills Disorders 6
Myocardial Reperfusion Injury 34
Neoplasm Invasiveness 127
Neoplasm Metastasis 138
Neoplastic Syndromes, Hereditary 48
PTEN Hamartoma Tumor Syndrome 1
Pancreatic Neoplasm 79
Polydactyly 93
Prostate cancer 172 5.0
Prostatic Intraepithelial Neoplasias 11
Prostatic Neoplasms 471
Proteus-Like Syndrome (disorder) 1
Pten Hamartoma Tumor Syndrome With Granu... 1 
Renal Cell Carcinoma 199
Reperfusion Injury 84
Sezary Syndrome 26
Skin cancer 37 1.0
Small cell carcinoma of lung 45
Squamous cell carcinoma of the head and ... 24 
Thyroid cancer, follicular 7
VACTERL Association With Hydrocephalus 2
Vater Association With Macrocephaly And ... 1 
acute quadriplegic myopathy 1,157
adult high grade glioma 2,148
atypical teratoid / rhabdoid tumor 4,369
glioblastoma 5,572
invasive ductal carcinoma 2,950
juvenile dermatomyositis 1,189
lung adenocarcinoma 2,713
lung cancer 4,466 1.0
medulloblastoma, large-cell 6,234
nasopharyngeal carcinoma 1,056
non-small cell lung cancer 2,798
oligodendroglioma 2,849
osteosarcoma 7,933
ovarian cancer 8,484
ovarian neoplasm 97
pancreatic cancer 2,300
pancreatic ductal adenocarcinoma liver m... 1,795 
tuberculosis 1,557

Expression

  Differential Expression (16)

Disease log2 FC p
oligodendroglioma -1.400 0.045
osteosarcoma -2.198 0.001
glioblastoma -1.600 0.000
atypical teratoid / rhabdoid tumor -1.200 0.000
medulloblastoma, large-cell -1.400 0.001
juvenile dermatomyositis 1.165 0.000
acute quadriplegic myopathy 1.171 0.000
pancreatic ductal adenocarcinoma liver m... -1.018 0.003
tuberculosis 1.400 0.000
non-small cell lung cancer -1.140 0.000
adult high grade glioma -1.500 0.000
lung adenocarcinoma -1.500 0.000
invasive ductal carcinoma -1.600 0.000
ovarian cancer -1.400 0.000
Breast cancer -1.300 0.000
pancreatic cancer 1.100 0.026

Synonym

Accession P60484 B2R904 F2YHV0 O00633 O02679 Q6ICT7
Symbols BZS
DEC
CWS1
GLM2
MHAM
TEP1
MMAC1
PTEN1
10q23del

Gene