Property Summary

NCBI Gene PubMed Count 24
PubMed Score 0.00
PubTator Score 12.23

Knowledge Summary


No data available


  Disease Sources (1)

Disease Target Count P-value
osteosarcoma 7933 3.12983744963653E-8
psoriasis 6685 3.07001134801653E-5
medulloblastoma, large-cell 6234 2.48383529743356E-4
atypical teratoid / rhabdoid tumor 4369 4.33841776411787E-4


  Differential Expression (4)

Disease log2 FC p
psoriasis -3.000 0.000
osteosarcoma -2.069 0.000
atypical teratoid / rhabdoid tumor -1.100 0.000
medulloblastoma, large-cell -1.700 0.000


Accession P59998 C9JWM7 E7ETI0 F6TTL5 O15509 Q6P0W5 Q96QJ3
Symbols ARC20


  Ortholog (12)

Species Source
Chimp OMA EggNOG
Mouse OMA EggNOG Inparanoid
Rat OMA Inparanoid
Cow OMA EggNOG Inparanoid
Opossum OMA EggNOG Inparanoid
Platypus OMA EggNOG Inparanoid
Chicken OMA EggNOG
Anole lizard OMA EggNOG Inparanoid
Xenopus OMA EggNOG Inparanoid
C. elegans OMA EggNOG Inparanoid
Fruitfly EggNOG Inparanoid
S.cerevisiae OMA EggNOG

Gene RIF (4)

23894563 Expression of the ARPC4 severely affects mycobacterium tuberculosis growth and suppresses immunogenic response in murine macrophages
23267127 we show cell line-specific differences in ARP2/3 complex subunit dependency on cell migratory potential, and suggest ARPC4 to be one of the key members of the ARP2/3 complex in pancreatic cancer.
23125841 Tandem affinity purification and mass spectrometry analysis identify 20kDa subunit 4 of actin related protein 2/3 complex (ARPC4), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells
17274980 We show that coronin 3 similar to other coronins interacts with the Arp2/3-complex and cofilin indicating that this family in general is involved in regulating Arp2/3-mediated events.

AA Sequence

EIDKEISEMKLSVNARARIVAEEFLKNF                                              141 - 168

Text Mined References (25)

PMID Year Title
25416956 2014 A proteome-scale map of the human interactome network.
23921388 2013 Identification and characterization of a novel human methyltransferase modulating Hsp70 protein function through lysine methylation.
23894563 2013 Expression of the ARPC4 subunit of human Arp2/3 severely affects mycobacterium tuberculosis growth and suppresses immunogenic response in murine macrophages.
23376485 2013 Proteomic analysis of podocyte exosome-enriched fraction from normal human urine.
23267127 2013 Silencing of the ARP2/3 complex disturbs pancreatic cancer cell migration.
20959098 2010 Molecular dynamics simulations of Arp2/3 complex activation.
20458337 MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
20404198 2010 An actin-filament-binding interface on the Arp2/3 complex is critical for nucleation and branch stability.
19056867 2009 Large-scale proteomics and phosphoproteomics of urinary exosomes.
18805923 2008 Molecular dynamics simulation and coarse-grained analysis of the Arp2/3 complex.