Tchem HUNK Hormonally up-regulated neu tumor-associated kinase

Protein Summary

Uniprot Accession IDs

• P57058

Gene Name

• HUNK

Ensembl ID

• ENST00000270112
• ENSP00000270112
• ENSG00000142149

Symbol

• MAKV

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.9
protein domain	0.73
gene perturbation	0.71
microRNA	0.7
PubMedID	0.65

Protein Classes

PANTHER Classes

Protein / Transferase / Kinase / Protein Kinase / Non-receptor Serine/threonine Protein Kinase / Hormonally Up-regulated Neu Tumor-associated Kinase

DTO Classes

Protein / Kinase / Protein Kinase / Camk Group / Camkl Family / Hunk Subfamily / Hormonally Up-regulated Neu Tumor-associated Kinase

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 33.96   (req: < 5)

Gene RIFs: 11   (req: <= 3)

Antibodies: 329   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 33.96   (req: >= 5)

Gene RIFs: 11   (req: > 3)

Antibodies: 329   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 1

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0