| Tbio | Heterogeneous nuclear ribonucleoprotein A3 |
Plays a role in cytoplasmic trafficking of RNA. Binds to the cis-acting response element, A2RE. May be involved in pre-mRNA splicing.
Comments
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Schizophrenia | 1160 | 0.0 | 0.0 |
| Disease | Target Count | P-value |
|---|---|---|
| malignant mesothelioma | 3232 | 7.6e-06 |
| medulloblastoma, large-cell | 6241 | 1.7e-05 |
| acute quadriplegic myopathy | 1158 | 3.3e-05 |
| dermatomyositis | 966 | 8.9e-05 |
| lung adenocarcinoma | 2716 | 2.1e-04 |
| psoriasis | 6694 | 3.0e-04 |
| ovarian cancer | 8520 | 9.1e-04 |
| osteosarcoma | 7950 | 1.2e-03 |
| autosomal dominant Emery-Dreifuss muscular dystrophy | 510 | 3.4e-03 |
| Waldenstrons macroglobulinemia | 765 | 1.2e-02 |
| group 3 medulloblastoma | 4104 | 1.3e-02 |
| Multiple myeloma | 1332 | 1.9e-02 |
| hereditary spastic paraplegia | 318 | 2.7e-02 |
| primary Sjogren syndrome | 735 | 3.5e-02 |
| Breast cancer | 3578 | 4.0e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Liver disease | 237 | 0.0 | 1.4 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Multiple endocrine neoplasia type 2A | 20 | 4.81 | 2.4 |
| Frontotemporal dementia | 51 | 3.523 | 1.8 |
| Multiple endocrine neoplasia type 2B | 17 | 3.218 | 1.6 |
| Amyotrophic lateral sclerosis | 451 | 3.111 | 1.6 |
| Disease | log2 FC | p |
|---|---|---|
| acute quadriplegic myopathy | 1.228 | 3.3e-05 |
| autosomal dominant Emery-Dreifuss muscul... | 1.030 | 3.4e-03 |
| Breast cancer | 1.900 | 4.0e-02 |
| dermatomyositis | 2.000 | 8.9e-05 |
| group 3 medulloblastoma | 1.100 | 1.3e-02 |
| hereditary spastic paraplegia | -1.006 | 2.7e-02 |
| lung adenocarcinoma | 1.017 | 2.1e-04 |
| malignant mesothelioma | 1.100 | 7.6e-06 |
| medulloblastoma, large-cell | 1.200 | 1.7e-05 |
| Multiple myeloma | 1.108 | 1.9e-02 |
| osteosarcoma | -1.114 | 1.2e-03 |
| ovarian cancer | -1.100 | 9.1e-04 |
| primary Sjogren syndrome | 1.100 | 3.5e-02 |
| psoriasis | -1.700 | 3.0e-04 |
| Waldenstrons macroglobulinemia | 1.600 | 1.2e-02 |
MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDP 1 - 70 QTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEY 71 - 140 NLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQSA 141 - 210 GSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGGNYGGG 211 - 280 PGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGS 281 - 350 FGGRSSGSPYGGGYGSGGGSGGYGSRRF 351 - 378 //
