Property Summary

NCBI Gene PubMed Count 169
Grant Count 231
R01 Count 119
Funding $17,312,234.58
PubMed Score 945.24
PubTator Score 204.73

Knowledge Summary

Patent

No data available

Expression

  Differential Expression (8)

Disease log2 FC p
non diabetic and post-ischemic heart fai... -1.300 0.002
medulloblastoma, large-cell 1.200 0.001
colon cancer -1.500 0.024
lung cancer -2.000 0.000
interstitial cystitis 3.500 0.000
ulcerative colitis 1.900 0.002
ovarian cancer 1.600 0.019
psoriasis 2.000 0.000

Synonym

Accession P51671 P50877 Q92490 Q92491
Symbols SCYA11

Gene

PDB

1EOT   2EOT   2MPM  

Gene RIF (144)

PMID Text
26907493 ANDV caused long-term elevated levels of eotaxin-1, IL-6, IL-8, IP-10, and VEGF-A that peaked 20-25 days after infection
26699196 co-cultures of KYSE-410 cells and cancer-associated fibroblasts (CAF) were investigated. Similar to SF, Has2 and Ccl5 were up-regulated and Ccl11 was down-regulated in CAF in co-culture.
26491210 The A allele in eotaxin 67 G/A polymorphism is associated with worse survival in CAD patients.
26359802 Findings demonstrate a link between CCL11 and primary Sjogren's syndrome disease activity and lymphoma.
26341115 increased amounts released by neutrophils from fibromyalgia patients
26324103 The results of this study suggested that eotaxin-1 as a novel modifier of Alzheimer's disease age at onset and open potential avenues for therapy.
26306920 Serum and urinary CCL11 were decreased in patients with prostate cancer compared with controls.
26270578 Eotaxin measured on the day of birth is useful for identifying extremely low birth weight infants at risk of bronchopulmonary dysplasia/death.
26241961 we identify higher levels of CRP, eotaxin and MCP-1 in serum of periodontitis patients
25645983 IL-1b can substantially stimulate the secretion of eotaxin and RANTES in nasal polyp-derived fibroblasts.
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AA Sequence

MKVSAALLWLLLIAAAFSPQGLAGPASVPTTCCFNLANRKIPLQRLESYRRITSGKCPQKAVIFKTKLAK      1 - 70
DICADPKKKWVQDSMKYLDQKSPTPKP                                                71 - 97
//

Text Mined References (169)

PMID Year Title
26907493 2016 Andes Hantavirus-Infection of a 3D Human Lung Tissue Model Reveals a Late Peak in Progeny Virus Production Followed by Increased Levels of Proinflammatory Cytokines and VEGF-A.
26699196 2016 Esophageal Squamous Cell Carcinoma Cells Modulate Chemokine Expression and Hyaluronan Synthesis in Fibroblasts.
26491210 2015 The Relation between eNOS -786 C/T, 4 a/b, MMP-13 rs640198 G/T, Eotaxin 426 C/T, -384 A/G, and 67 G/A Polymorphisms and Long-Term Outcome in Patients with Coronary Artery Disease.
26359802 2015 CXCL13 and CCL11 Serum Levels and Lymphoma and Disease Activity in Primary Sjögren's Syndrome.
26341115 2016 Altered release of chemokines by phagocytes from fibromyalgia patients: a pilot study.
26324103 2015 Whole-genome sequencing suggests a chemokine gene cluster that modifies age at onset in familial Alzheimer's disease.
26306920 2015 Is Eotaxin-1 a serum and urinary biomarker for prostate cancer detection and recurrence?
26270578 2015 Serum eotaxin-1 is increased in extremely-low-birth-weight infants with bronchopulmonary dysplasia or death.
26241961 2015 Increased Eotaxin and MCP-1 Levels in Serum from Individuals with Periodontitis and in Human Gingival Fibroblasts Exposed to Pro-Inflammatory Cytokines.
25645983 2015 Vitamin D decreases the secretion of eotaxin and RANTES in nasal polyp fibroblasts derived from Taiwanese patients with chronic rhinosinusitis with nasal polyps.
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