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Tbio
GPR15
G-protein coupled receptor 15

Protein Summary
Description
Probable chemokine receptor. Alternative coreceptor with CD4 for HIV-1 infection. This gene encodes a G protein-coupled receptor that acts as a chemokine receptor for human immunodeficiency virus type 1 and 2. The encoded protein localizes to the cell membrane. [provided by RefSeq, Nov 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000284311
  • ENSP00000284311
  • ENSG00000154165

Symbol
  • BOB
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
co-expressed gene
0.95
gene perturbation
0.77
cell type or tissue
0.67
phenotype
0.67
cell line
0.45


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 224.94   (req: < 5)
Gene RIFs: 23   (req: <= 3)
Antibodies: 364   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 224.94   (req: >= 5)
Gene RIFs: 23   (req: > 3)
Antibodies: 364   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0