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Tchem
PRLHR
Prolactin-releasing peptide receptor

Protein Summary
Description
Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing. PRLHR is a 7-transmembrane domain receptor for prolactin-releasing hormone (PRLH; MIM 602663) that is highly expressed in anterior pituitary (Ozawa et al., 2002 [PubMed 11923475]).[supplied by OMIM, Mar 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000239032
  • ENSP00000239032
  • ENSG00000119973
  • ENST00000636925
  • ENSP00000490073

Symbol
  • GPR10
  • GR3
  • GR3
  • GPR10
  • PrRPR
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.9
ligand (protein)
0.68
phenotype
0.54
cell line
0.5
molecular function
0.49


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.93   (req: < 5)
Gene RIFs: 12   (req: <= 3)
Antibodies: 267   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.93   (req: >= 5)
Gene RIFs: 12   (req: > 3)
Antibodies: 267   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 191
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0